Drug Discovery

The blueprint for a life-saving drug can often be found in the intricate, three-dimensional architecture of a single protein, yet viewing this structure with perfect clarity has remained a persistent challenge for modern science. For pharmaceutical researchers, this microscopic world is the

The advent of immunotherapy offered a powerful beacon of hope in the fight against advanced melanoma, yet for many patients and their families, that light has remained frustratingly out of reach. These revolutionary treatments, designed to unleash the body's own immune system against cancer, have

A concerning and rapid increase in bowel cancer diagnoses among younger adults has added a new layer of urgency to one of oncology's most persistent challenges: the ability of tumors to develop resistance to standard treatments. This growing crisis highlights a critical gap in medical science, as

With one in two women over the age of 50 expected to suffer a bone fracture due to osteoporosis, the race for more effective treatments has reached a critical juncture. In a landmark decision, the U.S. Food and Drug Administration (FDA) has officially qualified bone mineral density (BMD) as a

The journey of a new drug from laboratory concept to patient bedside is often paved with paradoxes, but rarely is the contradiction as stark as a medicine that successfully builds bone yet fails to stop it from breaking. This was the surprising outcome for setrusumab, a highly anticipated treatment

The persistence of devastating medical conditions like cancer recurrence and antibiotic resistance often stems not from a failure of the drug itself, but from the survival of a few rogue cells that defy treatment. These resilient "outlier" cells, which deviate from the population average, represent