Drug Discovery

VA Tests Semaglutide as a New Treatment for Alcoholism
Research & Development VA Tests Semaglutide as a New Treatment for Alcoholism

VA leadership has issued a cautionary warning against the off-label use of GLP-1 medications for alcoholism without strict medical supervision and oversight. This directive arrives just as the Charles George VA Medical Center in Asheville, North Carolina, spearheads a transformative Phase 3

Can Merck and SCRI Bridge the Gap in Oncology Trials?
Research & Development Can Merck and SCRI Bridge the Gap in Oncology Trials?

The strategic alliance between Merck and the Sarah Cannon Research Institute aims to transform oncology research by deploying a network of over 200 locations and 1,500 oncology physicians. This massive undertaking addresses a fundamental imbalance in modern medicine: while nearly eighty-five

Japan Approves Sevabertinib for HER2-Mutant Lung Cancer
Research & Development Japan Approves Sevabertinib for HER2-Mutant Lung Cancer

The SOHO-01 trial results highlight that gastrointestinal and skin-related issues such as diarrhea and rash are the most common side effects, which are generally considered manageable by clinicians. On August 24, 2026, Japan’s Ministry of Health, Labour and Welfare reached a landmark decision by

FDA Issues Second Hold on Regenxbio Hunter Syndrome Therapy
Research & Development FDA Issues Second Hold on Regenxbio Hunter Syndrome Therapy

Sponsors of CNS-directed gene therapies are now being urged to embed independent imaging review boards directly into their trial protocols to avoid similar regulatory failures. This directive follows the U.S. Food and Drug Administration's decision to issue a second clinical hold on Regenxbio’s

Do Brain Organoids Possess an Internal Developmental Clock?
Biotech & Bioprocessing Do Brain Organoids Possess an Internal Developmental Clock?

The discovery of a cell-intrinsic developmental clock suggests that laboratory-grown brain tissues record and recall their age regardless of their external environment. For years, scientists wondered if the maturation of human brain organoids was dictated by the nutrient-rich media of the petri

UC Davis Health CPMDS Leads AI-Driven Precision Medicine
Tech & Innovation UC Davis Health CPMDS Leads AI-Driven Precision Medicine

Dr. Colleen Clancy is pioneering the use of Optical Digital Twins to bridge the gap between complex biological data and individualized medical interventions. This mission stands at the heart of the Center for Precision Medicine and Data Sciences at UC Davis Health, where the convergence of advanced

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