Drug Discovery

First Topical CRISPR Therapy Treats Genetic Skin Disease
Research & Development First Topical CRISPR Therapy Treats Genetic Skin Disease

For individuals living with debilitating genetic skin disorders, effective treatments have remained elusive, often limited to managing symptoms rather than addressing the root cause encoded in their DNA. A groundbreaking development from researchers at the University of British Columbia and the

New Therapies Target Cancer's Amino Acid Metabolism
Research & Development New Therapies Target Cancer's Amino Acid Metabolism

Recent breakthroughs are fundamentally recasting our understanding of cancer, shifting the focus from a disease of uncontrolled cell division to one characterized by a profoundly altered and ravenous metabolism. At the heart of this new perspective is the discovery that malignant cells harbor a

New Trials Are Reshaping Bladder Cancer Care
Research & Development New Trials Are Reshaping Bladder Cancer Care

The treatment paradigm for bladder cancer is undergoing a seismic shift, as a new wave of clinical research moves beyond traditional protocols to pioneer a more integrated, intelligent, and immune-focused approach to care. This evolution is not merely about refining existing methods but about

FDA Partially Lifts Hold on Intellia CRISPR Trial
Research & Development FDA Partially Lifts Hold on Intellia CRISPR Trial

Today we’re joined by Ivan Kairatov, a biopharma expert with deep experience in drug development and the intricate dance between innovation, regulation, and market perception. We'll be dissecting the recent developments with Intellia Therapeutics, a pioneer in CRISPR gene editing. The company has

What Is the Double-Edged Sword of Cancer Fibroblasts?
Research & Development What Is the Double-Edged Sword of Cancer Fibroblasts?

Within the intricate ecosystem of a tumor, cancer cells are far from acting alone; they are surrounded by a complex network of supporting cells that form the tumor microenvironment. Among these collaborators, cancer-associated fibroblasts (CAFs) have emerged as particularly influential players.

Can AI Stop Metabolic Disease Before It Starts?
Research & Development Can AI Stop Metabolic Disease Before It Starts?

The global surge in metabolic diseases presents one of the most significant public health challenges of our time, with conditions like diabetes affecting more than one in five adults in certain regions, such as the Middle East. This escalating crisis has traditionally been met with a reactive

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