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Tag: cell therapy


Cell and Gene Therapy, Industry, News

Catalent Appoints Open Innovation, Biologics, Cell and Gene Therapy VP

November 19, 2020

Via: Contract Pharma

Catalent has appointed Behzad Mahdavi, Ph.D., MBA, as Vice President of Open Innovation, Biologics, Cell and Gene Therapy. In this new role, Dr. Mahdavi will join a team of experts in Catalent’s Science and Technology Group that works with customers […]


Industry, News, Vaccines

Immune-Boosting Components Double the Effectiveness of Melanoma Vaccine Candidate in Phase II Trial

November 18, 2020

Via: Genetic Engineering and Biotechnology News

A vaccine created to prevent the recurrence of the deadly skin cancer melanoma is about twice as effective when patients also receive two components that boost the number and effectiveness of immune system dendritic cells (DCs), according to the results […]


Cell and Gene Therapy, Industry

Boosting Capabilities in Gene and Cell Therapy Bioprocessing

November 17, 2020

Via: Genetic Engineering and Biotechnology News

A new company has been founded to supply software for managing cell & gene therapy manufacturing. Autolomous, founded in February 2019, has already secured four different clients whom they hope to assist with digitizing and streamlining their workflows. “There’s a […]


Clinical Trials, Research and Development

Novel Cell Analysis Tool Bridges In Situ Microscopy and Single Cell Omics

November 12, 2020

Via: Genetic Engineering and Biotechnology News

Scientists have developed a new method that allows them to select individual cells from a population that is growing on the surface of a laboratory dish, and then study their contents using DNA and protein sequencing technologies to analyze the […]


FDA, Regulations

FDA Places New CMC Demands on bluebird’s Sickle Cell Treatment

November 5, 2020

Via: BioSpace

Shares of bluebird bio fell more than 17% in premarket trading after the company announced late Wednesday that its sickle cell disease gene therapy treatment will not be submitted to the U.S. Food and Drug Administration (FDA) for two more […]


Cell and Gene Therapy, Industry

Scientists use gene therapy to regenerate damaged optic nerve fibers

November 5, 2020

Via: Medical News

Scientists have used gene therapy to regenerate damaged nerve fibers in the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the leading causes of blindness worldwide. Axons – nerve fibers – in […]


Cell and Gene Therapy, Industry

Treating multiple sclerosis with an antigen-specific cell therapy

November 4, 2020

Via: FierceBiotech

Existing multiple sclerosis therapies systematically modulate the immune system to dampen its erroneous attack on the protective myelin sheaths around nerve cells, which is the hallmark of the autoimmune disease. But this approach puts patients at a higher risk of […]


News

Samsung Biologics Establishes Partnership with China Biotech GeneQuantum Healthcare to Collaborate on ADC Development

November 2, 2020

Via: BioSpace

Samsung Biologics (207940.KS) has entered into a strategic partnership with GeneQuantum Healthcare, a China biotech company, to jointly develop an antibody drug conjugate (ADC) for the treatment of non-small-cell lung carcinoma (NSCLC), triple-negative breast cancer (TNBC), and other solid tumors. […]


Cell and Gene Therapy, Clinical Trials, Industry, Research and Development

Scientists Map Sensitivity of Thousands of Genes to Chemical Exposure

November 2, 2020

Via: Genetic Engineering and Biotechnology News

Scientists at the University of Massachusetts, Amherst, have used what they claim is an unprecedented objective approach to identify which genes and molecular pathways— including mechanisms involving aging, lipid metabolism, and autoimmune disease—are most sensitive to chemical exposure. Headed by […]


Cell and Gene Therapy, Industry

Catalent to Acquire Bone Therapeutics’ Cell Therapy Mfg. Facility

October 29, 2020

Via: Contract Pharma

Catalent has signed an agreement with Bone Therapeutics to acquire its cell therapy manufacturing subsidiary, Skeletal Cell Therapy Support SA (SCTS), including all of its assets located in Gosselies, Belgium. Catalent will purchase the shares of SCTS, currently held by […]


Cell and Gene Therapy, Industry

Lysogene Confirms Child’s Death in Phase II/III Gene Therapy Trial

October 26, 2020

Via: Genetic Engineering and Biotechnology News

A five-year-old girl with Mucopolysaccharidosis Type IIIA (MPS IIIA) has died in the Phase II/III AAVance clinical trial (NCT03612869), designed to evaluate the efficacy of Lysogene’s gene therapy candidate LYS-SAF302 in improving or stabilizing the neurodevelopmental state of MPS IIIA […]


Clinical Trials, Research and Development

SARS-CoV-2 Infection Modeled in 3-D Stem Cell Culture Model

October 23, 2020

Via: Genetic Engineering and Biotechnology News

Understanding how SARS-CoV-2 infection damages the lungs is paramount to developing better treatments. Now, “mini-lungs” grown from tissue donated to Cambridge hospitals has provided a team of scientists with important insights into how COVID-19 damages the lungs. In new work, […]