Drug Discovery

Obesity Leaves Years-Long Epigenetic Memory in T Cells
Research & Development Obesity Leaves Years-Long Epigenetic Memory in T Cells

Long after scales celebrate a hard-won weight loss, the immune system can keep score in subtler ways, storing traces of past obesity inside helper T cells as molecular marks that linger and continue to shape health in the background. This emerging insight reframes obesity as more than excess fat;

Can AI Find BBB-Ready, mTOR-Free Autophagy Enhancers for AD?
Tech & Innovation Can AI Find BBB-Ready, mTOR-Free Autophagy Enhancers for AD?

Decades of Alzheimer’s drug programs faltered because promising molecules either nudged the wrong levers of cell biology or stalled at the brain’s front door, and the result has been a cycle of costly starts and quiet sunsets that underscored how hard it is to increase autophagic clearance without

FDA OKs J&J’s Icotyde, First Oral IL-23 Psoriasis Drug
Research & Development FDA OKs J&J’s Icotyde, First Oral IL-23 Psoriasis Drug

Clinic days often hinge on one question patients ask with a mix of hope and hesitation: is there a pill that can match the clearing power of injections without the needles, the storage hassles, or the crowded appointment calendar. That answer just shifted as the FDA cleared Johnson & Johnson’s

Can Engineered BEVs Be the Next Weapon Against AMR?
Research & Development Can Engineered BEVs Be the Next Weapon Against AMR?

Relentless rises in drug-resistant infections have turned routine care into a negotiation with risk that standard antibiotics too often lose, and the search for smarter countermeasures has shifted to tools built by biology itself. Bacterial extracellular vesicles (BEVs) sit at that inflection

Can miR-181d Revolutionize Glioblastoma Treatment?
Research & Development Can miR-181d Revolutionize Glioblastoma Treatment?

The diagnostic weight of Glioblastoma Multiforme has remained largely unchanged for decades, despite the rapid acceleration of genetic sequencing and molecular mapping in other oncology sectors. This malignancy represents the primary challenge in adult oncology due to its infiltrating nature and

Atomic Map of Vibrio Bacteria Helps Disarm Deadly Infections
Research & Development Atomic Map of Vibrio Bacteria Helps Disarm Deadly Infections

The warming of coastal waters along the Atlantic and Mediterranean has accelerated the proliferation of Vibrio bacteria, creating an urgent public health crisis that demands immediate scientific intervention. As these pathogens thrive in rising temperatures, traditional medical approaches find

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