Drug Discovery

Nanoparticles Prime Resistant Tumors for Immunotherapy
Research & Development Nanoparticles Prime Resistant Tumors for Immunotherapy

A significant portion of cancer patients do not respond to immunotherapy because their tumors are immunologically inactive, but a groundbreaking collaborative study from Cornell University researchers has unveiled a remarkable solution using ultrasmall fluorescent silica nanoparticles, known as

Fentanyl Overdose Vaccine Enters First Human Trials
Research & Development Fentanyl Overdose Vaccine Enters First Human Trials

In the relentless battle against the opioid epidemic, medical intervention has largely been a reactive measure, but a pioneering vaccine now entering its first human trials aims to fundamentally shift this paradigm from response to prevention. Developed by researchers at the University of Houston

Study Finds Vitamin A Derivative Blocks Cancer Immunity
Research & Development Study Finds Vitamin A Derivative Blocks Cancer Immunity

New research from Princeton University’s Ludwig Institute for Cancer Research has untangled the complex and often harmful relationship between a vitamin A derivative and the body's ability to fight cancer, resolving a long-standing paradox about vitamin A's role in oncology and introducing a

Can a Dual-Action Nanodrug Defeat Lethal Cancers?
Research & Development Can a Dual-Action Nanodrug Defeat Lethal Cancers?

A significant new research initiative is confronting two of the most formidable and lethal malignancies, pancreatic and lung cancer, with a highly innovative therapeutic strategy. Led by Professor Wei Gao at the University of Houston College of Pharmacy, a groundbreaking project has secured a

Will Alumis' Pill Topple Psoriasis Market Leaders?
Research & Development Will Alumis' Pill Topple Psoriasis Market Leaders?

In the fast-evolving world of immunology, the race to develop a highly effective oral treatment for psoriasis has reached a fever pitch. With the recent success of Alumis's Phase 3 trials for envudeucitinib, the landscape is poised for a significant shift. We sat down with biopharma expert Ivan

Intellicule Awarded NIH Grant to Advance Drug Discovery
Tech & Innovation Intellicule Awarded NIH Grant to Advance Drug Discovery

The blueprint for a life-saving drug can often be found in the intricate, three-dimensional architecture of a single protein, yet viewing this structure with perfect clarity has remained a persistent challenge for modern science. For pharmaceutical researchers, this microscopic world is the

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