Tag: clinical trials

October 14, 2021

The FDA has cleared Keytruda in combination with chemotherapy – with or without bevacizumab – for patients with persistent, recurrent or metastatic cervical cancer whose tumours express PD-L1. In the Phase III KEYNOTE-826 trial in this patient population, Keytruda plus […]

October 12, 2021

The Dana-Farber Cancer Institute has reportedly barred trustees from newly investing in biotechs created to license its science, leading to the resignation of board members including a co-founder of C4 Therapeutics. Under the old policy, trustees could invest in startups […]

October 4, 2021

The FDA granted BTD based on data from the DESTINY-Breast03 phase 3 trial presented during the European Society for Medical Oncology (ESMO) Congress 2021. The results of the phase 3 trial showed that Enhertu reduced the risk of disease progression […]

September 28, 2021

ViroCell Biologics and Great Ormond Street Hospital for Children (GOSH) have today announced a new partnership that will immediately address the global viral vector manufacturing bottleneck for clinical trials. Viral vectors are high-value delivery vehicles used to make cell and […]

September 28, 2021

Myeloperoxidase (MPO) inhibitor verdiperstat was no better than placebo in the M-STAR trial in patients with MSA, and looks likely to be abandoned for this indication. It’s not the end of the line for the drug, which Biohaven picked up […]

September 27, 2021

The grant from the Israel-US Binational Industrial Research and Development (BIRD) Foundation will go towards the further development of the platform, which automates the conduct of trials in a bid to reduce the cost, time, and resources used running them. […]

September 24, 2021

If you have cancer and you think coronavirus vaccines may do you little good, don’t let your hesitation stop you from getting the shots: A pair of clinical trials finds that patients’ immune systems ramped up after vaccination. The findings […]

September 23, 2021

FDA granted accelerated approval to Seagen and Genmab’s Tivdak (tisotumab vedotin-tftv), a tissue factor-directed antibody and microtubule inhibitor conjugate, according to a Sept. 20, 2021, FDA press release. According to the Seagen company press release, Tivdak is the first and […]

September 17, 2021

A CRISPR-Cas9 gene editing technology that has shown promise in clearing HIV from mice is headed into human testing. Excision BioTherapeutics will usher the CRISPR-based therapy EBT-101 into clinical trials after the FDA cleared an investigational new drug application, according […]

September 9, 2021

Obsidian Therapeutics has raked in $115 million to realize the long-unfulfilled therapeutic promise of tumor-infiltrating lymphocytes (TILs). The series B gives Obsidian a shot at showing whether freeing TILs from IL-2 can finally unleash power that research has hinted at […]

September 8, 2021

The deal with see Adaptimmune receive $150m upfront, another $150m over the next five years and then milestone payments potentially exceeding $3bn in aggregate sales, as well as royalties. Unlike other leaders in next-generation cell therapies, the partners will use […]

August 30, 2021

An estimated 8% of Americans have an autoimmune disease, including a disproportionate number of people in the minority communities most severely impacted by COVID-19. In addition, higher rates of severe COVID-19 and death have been reported in people with autoimmune […]