Tag: clinical trials

November 30, 2022

WHIM syndrome is a rare, inherited, combined immunodeficiency disease that inhibits the body’s ability to fight infections. In most patients, this is caused by over-signalling of the CXCR4/CXCL12 pathway, resulting in reduced mobilisation and trafficking of white blood cells from […]

November 30, 2022

The results of research headed by a team at Shanghai Jiao Tong University have identified formic acid as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease (AD). The findings could potentially pave the way for inexpensive and convenient […]

November 30, 2022

Researchers from Flinders University and the South Australian Health and Medical Research Institute (SAHMRI) have been studying ways to uncover potential new drug therapies for the common and lethal brain cancer, glioblastoma. In a new study, the team discovered that […]

November 28, 2022

When pregnant women contract COVID-19, one in 10 will have moderate, severe or even critical symptoms, a new study finds. So it’s important they get their COVID vaccines, experts say. “Given that patients in all trimesters of pregnancy are susceptible […]

November 28, 2022

There are over 52,000 cases of prostate cancer each year in the UK alone, with over 15,000 new cases of metastatic prostate cancer confirmed annually. The approval comes after the presentation of data from the ARASENS phase 3 clinical trial […]

November 22, 2022

Squamous cell carcinoma (SqCC) is the second most prevalent type of lung cancer. However, treatment options for these patients remain limited and have remained largely unchanged over decades. Now, a new study by researchers at the Garvan Institute of Medical […]

November 22, 2022

The results of a study by researchers at Hokkaido University’s Faculty of Medicine have shown how composition of the gut microbiome is crucial to driving a process known as granulopoiesis that replenishes neutrophil counts in the blood of mice following […]

November 22, 2022

The complex networks of fluid-filled tubes and loops that exist in human organs have three-dimensional structures whose connections vary, depending on the organ. How these connections and topology develop during the development of an embryo, remains unclear. Now, using tissue […]

November 21, 2022

The world responded to the crisis at unprecedented speed, as leaders and experts focused on different ways to operate and succeed within the constraints of a new dynamic. One standout success we have all benefitted from is vaccine development, with […]

November 21, 2022

In a study published in the journal Cell on November 18, a team led by scientists at Weill Cornell Medicine, and the National Institutes of Health (NIH) have isolated an uncommon and ultrapotent antibody that can neutralize the pathogenic zika […]

November 21, 2022

The brains of people with Down syndrome (DS) develop the same neurodegenerative tangles and plaques that are associated with Alzheimer’s disease (AD), and individuals with DS commonly exhibit signs of the neurodegenerative disorder in their forties or fifties. A new […]

November 18, 2022

Scientists at the Johns Hopkins Kimmel Comprehensive Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy report that they successfully trained a machine learning algorithm to predict, in hindsight, which patients with melanoma would respond to treatment and which would […]

November 18, 2022

Clostridioides difficile is a bacterium that causes severe intestinal illness, but can be difficult to study and treat, and represents a significant public health issue. Studies in mice and in children carried out by researchers at Children’s Hospital of Philadelphia […]

November 18, 2022

A new study from New York Eye and Ear Infirmary of Mount Sinai demonstrates that patients with a specific form of age-related macular degeneration (AMD) may have either underlying heart damage from heart failure and heart attacks, or advanced heart […]

November 17, 2022

The committee voted nine to four in favour of Xphozah – a phosphate absorption inhibitor – to be administered as a monotherapy for treating this patient population, and voted ten to two, with one abstention, for the drug’s use alongside […]

November 16, 2022

The U.S. Food and Drug Administration approved the combination of tremelimumab (Imjudo) plus durvalumab (Imfinzi) and platinum-based chemotherapy for adult patients with metastatic non-small cell lung cancer with no sensitizing epidermal growth factor receptor mutation or anaplastic lymphoma kinase genomic […]

November 16, 2022

Babies born via cesarean section may not mount as strong an immune response after some childhood vaccines compared to babies delivered vaginally, researchers suggest. Antibody levels can be checked in blood or saliva, and babies born vaginally had higher levels […]

November 16, 2022

The study of GSK3036656 – an inhibitor of the bacterial enzyme leucyl t-RNA synthetase (LeuRS) – showed that 14 days’ treatment with a low once-daily dose showed it was able to kill Mycobacterium tuberculosis in patients with drug-susceptible pulmonary tuberculosis, […]

November 15, 2022

A study led by researchers at NYU Grossman School of Medicine and UC San Diego Moores Cancer Center has found that patients with head and neck cancer who have more genetic material at a specific region on chromosome 9 in […]

November 15, 2022

Thankfully, the world has mostly returned to normal and the virus will hopefully be a thing of the past in the near future. The pandemic leaves myriad economic, social, health, and psychological scars in its wake. It caused intense suffering […]