Tag: clinical trials

September 18, 2020

A SARS-CoV-2 infection begins when the virus’s spike proteins bind to ACE2 cell surface receptors, enabling the virus to infect human cells. This key event of the receptor binding is followed by fusion of the virus and cell membranes to […]

September 14, 2020

Immune reactions caused by vaccination can help protect the organism, or sometimes may aggravate the condition. It is especially important now when multiple vaccines against COVID-19 are being developed. The top immunologists analyse types of immune response to predict what […]

September 14, 2020

Scientists at the University of Maryland School of Medicine (UMSOM) say they have conducted a study that has determined the role that a critical protein plays in the development of hair cells which are vital for hearing. Some of these […]

September 11, 2020

New York-based Intra-Cellular Therapies announced the pricing of its underwritten IPO of 4,750,000 shares at $24 per share, in hopes of raising about $106.5 million. On September 9, the company announced positive topline results from its Phase III Study 402 […]

September 4, 2020

BriaCell Corp. (“BriaCell” or the “Company”) (TSX-V:BCT) (OTCQB:BCTXF), a clinical-stage biotechnology company specializing in targeted immunotherapy for advanced breast cancer, is announcing that it has received a research grant from the Wiseman Cancer Research Foundation, a 501c(3) nonprofit organization based […]

September 3, 2020

CNS PHARMACEUTICALS AG, Inc. (NASDAQ: CNSP) (“CNS” or the “Company”), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the central nervous system, today provides an update on progress for the U.S. manufacturing […]

September 3, 2020

Alzheimer’s disease is a progressive form of dementia. When toxic proteins like beta-amyloid and tau accumulate in the brain, they form plaques and tangles. Researchers have been focusing on how brain plaque contributes to Alzheimer’s disease and what role they […]

September 2, 2020

City of Hope scientists have combined two potent immunotherapies — an oncolytic virus and chimeric antigen receptor (CAR) T cell therapy — to target and eradicate solid tumors that are otherwise difficult to treat with CAR T therapy alone, according […]

September 1, 2020

The patient experience is an important consideration in trial design. Historically, the clinical trial process runs from the top-down and is heavily controlled by clinical settings and subject to strict validation rules for data gathering and analysis. However, the data […]

September 1, 2020

Experimental drugs face steep odds. According to the Pharmaceutical Research and Manufacturers of America (PhRMA), out of every 5,000 to 10,000 compounds that enter the discovery and development pipeline, just 5 enter clinical trials, and only 1 receives approval. Other […]

August 25, 2020

Solid tumors are notoriously difficult to treat and often put children into a high-risk category as tumors like neuroblastoma, Ewing sarcoma, and rhabdomyosarcoma in these patients often don’t respond to conventional therapies. Chemotherapy given orally or intravenously generally does not […]

August 17, 2020

Although minorities are paying a disproportionate price in the rate of COVID-19 illnesses and deaths, they are underrepresented in clinical trials, a new study finds. The researchers call upon the government, medical journals and funders of research to make sure […]