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Tag: clinical trials


Clinical Trials, Research and Development

SARS-CoV-2 Spike Protein Forms Ten Distinct Structures with ACE2

September 18, 2020

Via: Genetic Engineering and Biotechnology News

A SARS-CoV-2 infection begins when the virus’s spike proteins bind to ACE2 cell surface receptors, enabling the virus to infect human cells. This key event of the receptor binding is followed by fusion of the virus and cell membranes to […]


Clinical Trials, Research and Development

Which immune response could cause a vaccine against COVID-19?

September 14, 2020

Via: World Pharma News

Immune reactions caused by vaccination can help protect the organism, or sometimes may aggravate the condition. It is especially important now when multiple vaccines against COVID-19 are being developed. The top immunologists analyse types of immune response to predict what […]


Clinical Trials, Research and Development

Protein Identified for New Hearing Hair Cell Development

September 14, 2020

Via: Genetic Engineering and Biotechnology News

Scientists at the University of Maryland School of Medicine (UMSOM) say they have conducted a study that has determined the role that a critical protein plays in the development of hair cells which are vital for hearing. Some of these […]


Clinical Trials, Research and Development

Biotech IPOs: Intra-Cellular Therapies, 10x Genomics and Spero Therapeutics

September 11, 2020

Via: BioSpace

New York-based Intra-Cellular Therapies announced the pricing of its underwritten IPO of 4,750,000 shares at $24 per share, in hopes of raising about $106.5 million. On September 9, the company announced positive topline results from its Phase III Study 402 […]


Clinical Trials, Research and Development

BriaCell Awarded Research Grant from Wiseman Cancer Research Foundation

September 4, 2020

Via: BioSpace

BriaCell Corp. (“BriaCell” or the “Company”) (TSX-V:BCT) (OTCQB:BCTXF), a clinical-stage biotechnology company specializing in targeted immunotherapy for advanced breast cancer, is announcing that it has received a research grant from the Wiseman Cancer Research Foundation, a 501c(3) nonprofit organization based […]


Clinical Trials, Manufacturing, Research and Development

CNS Pharmaceuticals Announces US Drug Manufacturing Milestones

September 3, 2020

Via: BioSpace

CNS PHARMACEUTICALS AG, Inc. (NASDAQ: CNSP) (“CNS” or the “Company”), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the central nervous system, today provides an update on progress for the U.S. manufacturing […]


Clinical Trials, Research and Development

Alzheimer’s Immune Response Interactions Revealed

September 3, 2020

Via: Genetic Engineering and Biotechnology News

Alzheimer’s disease is a progressive form of dementia. When toxic proteins like beta-amyloid and tau accumulate in the brain, they form plaques and tangles. Researchers have been focusing on how brain plaque contributes to Alzheimer’s disease and what role they […]


Cell and Gene Therapy, Clinical Trials, Industry, Research and Development

City of Hope Scientists Use Two Powerful Immunotherapies to Eradicate Solid Tumors

September 2, 2020

Via: BioSpace

City of Hope scientists have combined two potent immunotherapies — an oncolytic virus and chimeric antigen receptor (CAR) T cell therapy — to target and eradicate solid tumors that are otherwise difficult to treat with CAR T therapy alone, according […]


Clinical Trials, Research and Development

Virtualizing clinical trials to bring trials closer to patients

September 1, 2020

Via: Pharma IQ

The patient experience is an important consideration in trial design. Historically, the clinical trial process runs from the top-down and is heavily controlled by clinical settings and subject to strict validation rules for data gathering and analysis. However, the data […]


Industry, Pharma

Drug Targets Identified More Discerningly

September 1, 2020

Via: Genetic Engineering and Biotechnology News

Experimental drugs face steep odds. According to the Pharmaceutical Research and Manufacturers of America (PhRMA), out of every 5,000 to 10,000 compounds that enter the discovery and development pipeline, just 5 enter clinical trials, and only 1 receives approval. Other […]


Clinical Trials, Research and Development

Advanced Solid Tumor Prodrug Developed

August 25, 2020

Via: Genetic Engineering and Biotechnology News

Solid tumors are notoriously difficult to treat and often put children into a high-risk category as tumors like neuroblastoma, Ewing sarcoma, and rhabdomyosarcoma in these patients often don’t respond to conventional therapies. Chemotherapy given orally or intravenously generally does not […]


Clinical Trials, Research and Development

COVID-19 Clinical Trials Lack Diversity, Researchers Say

August 17, 2020

Via: Drugs.com

Although minorities are paying a disproportionate price in the rate of COVID-19 illnesses and deaths, they are underrepresented in clinical trials, a new study finds. The researchers call upon the government, medical journals and funders of research to make sure […]