Precision Medicine

High-Dimensional Immune Profiling – Review
Tech & Innovation High-Dimensional Immune Profiling – Review

Missed by the very blood tests meant to reveal them, too many testicular cancers slip through diagnostic nets just when speed matters most for adolescents and young adults facing life-shaping treatment choices. That gap is precisely what a new high-dimensional immune profiling approach set out to

Can a Single RAD52 Ring Guide BRCA-Selective Cancer Drugs?
Research & Development Can a Single RAD52 Ring Guide BRCA-Selective Cancer Drugs?

Nineteen protein subunits arranged in a near-perfect circle gripped a frayed DNA end, and that spare geometry—simple, symmetric, and relentless—reshaped how a critical cancer target might be stopped. The ring belonged to Mgm101, a yeast mitochondrial homolog of human RAD52, and under a convergence

Obesity Leaves Years-Long Epigenetic Memory in T Cells
Research & Development Obesity Leaves Years-Long Epigenetic Memory in T Cells

Long after scales celebrate a hard-won weight loss, the immune system can keep score in subtler ways, storing traces of past obesity inside helper T cells as molecular marks that linger and continue to shape health in the background. This emerging insight reframes obesity as more than excess fat;

Is UC San Diego Leading West Coast AI-Robotic Spine Surgery?
Tech & Innovation Is UC San Diego Leading West Coast AI-Robotic Spine Surgery?

Spine surgeons at UC San Diego Health just turned a complex, high-stakes operation into a choreographed, data-driven performance that put the West Coast on notice. The institution’s first spine surgery using a fully integrated robotic, AI-enabled platform was more than a successful case; it was a

FDA OKs J&J’s Icotyde, First Oral IL-23 Psoriasis Drug
Research & Development FDA OKs J&J’s Icotyde, First Oral IL-23 Psoriasis Drug

Clinic days often hinge on one question patients ask with a mix of hope and hesitation: is there a pill that can match the clearing power of injections without the needles, the storage hassles, or the crowded appointment calendar. That answer just shifted as the FDA cleared Johnson & Johnson’s

Can Hyperbaric Oxygen Help or Hinder Glioblastoma Therapy?
Tech & Innovation Can Hyperbaric Oxygen Help or Hinder Glioblastoma Therapy?

Oxygen can sharpen the sword or feed the fire in glioblastoma therapy, and hyperbaric dosing, timing, and biology together decide which edge cuts and whether treatment harms or helps. This research summary examines how hyperbaric oxygen therapy (HBOT) might both strengthen and undermine standard

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