Observations of immune system organoids in orbit help explain why human immune responses weaken in space, providing insights that could lead to new treatments for autoimmune diseases on Earth. The cultivation of miniature human tissues, known as organoids, aboard the International Space Station
The SLICeVLP system decouples guide RNA delivery from Cas9 protein delivery to enable large-scale pooled CRISPR screening in primary human macrophages for the first time. This technological leap addresses a longstanding bottleneck in the field of immunotherapy, where the focus has historically
Establishing a more translationally aligned approach through cross-sector collaboration is essential for identifying neurological risks before a drug reaches human clinical trials. The central nervous system remains the most daunting frontier in drug development due to its sheer structural
In addition to the recent NCI renewal, the UC Davis Medical Center has maintained its ranking as the top hospital in the Sacramento area for fifteen consecutive years according to national reports. This sustained excellence reached a new milestone today as the National Cancer Institute officially
Historical failures in the vitiligo pipeline, such as the cancellation of the AC##4 trial in 2016, highlight the difficulty of establishing a global site network. The recent publication of the Viti-Up Phase 3 clinical trial results in The Lancet marks a transformative moment for dermatologic
When levels of miR-342 drop, the E2F genetic pathway is unleashed, signaling disseminated cancer cells to begin the rapid multiplication required to form tumors. This mechanism serves as a terrifying catalyst for triple-negative breast cancer, a subtype that has historically defied the precision
