In early 2023, the FDA's announcement of a shortage of two critical generic platinum chemotherapy drugs, cisplatin and carboplatin, alarmed the medical community. These drugs have been essential in the treatment of various advanced cancers for over 30 years, particularly lung, head and neck,
Advancements in cancer therapy have brought significant hope, especially with immune checkpoint blockades (ICBs), providing a groundbreaking treatment strategy for advanced cancers. Despite this, the effectiveness of ICBs has often been thwarted by therapeutic resistance, which renders
Autoimmune encephalitis (AE), a condition where the body's immune system turns against the brain, affects approximately one-third of global encephalitis cases and often leads to debilitating symptoms, including seizures, cognitive impairment, and motor dysfunctions. Despite advancements in
The International Antiviral (formerly AIDS) Society-USA (IAS-USA) has unveiled comprehensive international guidelines for the treatment and prevention of HIV, coinciding with the observance of World AIDS Day on December 1, 2024. These guidelines were meticulously developed by a panel of volunteer
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), previously known as nonalcoholic fatty liver disease, has become a major global health concern. Characterized by hepatic steatosis and associated with at least one cardiometabolic risk factor such as type 2 diabetes mellitus (T2DM),
Imagine a world where Alzheimer's disease and frontotemporal dementia could be combated not with costly and sometimes harmful treatments, but with vaccines specially designed to target specific proteins without causing inflammation. This innovative approach is currently being explored by