Clinical Safety

How Is mpMRI Changing Prostate Cancer Diagnostics?
Tech & Innovation How Is mpMRI Changing Prostate Cancer Diagnostics?

The historical reliance on systematic transrectal biopsies carried a non-negligible risk of sepsis and life-threatening systemic infections for many asymptomatic patients. This traditional pathway often forced a clinical confrontation with potential complications before the severity of the

How Can AI and Digital Tools Improve CNS Drug Safety?
Research & Development How Can AI and Digital Tools Improve CNS Drug Safety?

Establishing a more translationally aligned approach through cross-sector collaboration is essential for identifying neurological risks before a drug reaches human clinical trials. The central nervous system remains the most daunting frontier in drug development due to its sheer structural

Annie Jacobsen’s Biological War Warns of Global Bio-Threats
Management & Regulatory Annie Jacobsen’s Biological War Warns of Global Bio-Threats

The proliferation of over one thousand high-containment laboratories in the United States since 9/11 has paradoxically increased the mathematical probability of a catastrophic accident. This startling statistic serves as the foundation for Annie Jacobsen’s investigation into the burgeoning threat

Can Upadacitinib Redefine the Regulatory Path for Vitiligo?
Research & Development Can Upadacitinib Redefine the Regulatory Path for Vitiligo?

Historical failures in the vitiligo pipeline, such as the cancellation of the AC##4 trial in 2016, highlight the difficulty of establishing a global site network. The recent publication of the Viti-Up Phase 3 clinical trial results in The Lancet marks a transformative moment for dermatologic

Bioengineered Conduits Show Promise for Coronary Bypass Surgery
Research & Development Bioengineered Conduits Show Promise for Coronary Bypass Surgery

A major hurdle in cardiac surgery is the compliance mismatch between stiff artificial tubes and flexible arteries, which creates turbulent blood flow and eventual graft blockage. This fundamental discrepancy has long prevented the widespread adoption of synthetic bypass grafts, as the sudden change

VA Expands Electronic Health Record System Across Indiana
Tech & Innovation VA Expands Electronic Health Record System Across Indiana

Healthcare providers in Indianapolis and Fort Wayne are now engaging in peer-to-peer knowledge sharing to master the nuances of the new electronic health record system in real-time clinical settings. This rollout marks a defining moment for the Department of Veterans Affairs as it integrates the

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