Top

Category: Clinical Trials


Clinical Trials, Research and Development

How the digital front door benefits clinical trial patients, clinicians and sponsors

May 22, 2023

Via: Biopharma Dive

Opening the digital front door to clinical trials means creating a great user experience for patients, clinicians and ultimately sites and sponsors. As anyone in healthcare knows all too well, it has historically been much easier said than done. However, […]


Clinical Trials, Research and Development

Moderna reports ‘encouraging’ early data for one of its rare disease medicines

May 19, 2023

Via: Biopharma Dive

Moderna said Friday that one of its rare disease drug programs showed promise in its first clinical trials, according to an early look at the data. The drug is meant to treat propionic acidemia, an uncommon genetic disorder that causes […]


Clinical Trials, Research and Development

GSK’s five-in-one meningococcal vaccine candidate shows promise in phase 3 trial

May 15, 2023

Via: PMLiVE

Preliminary results for the MenABCWY candidate were presented by the company at the European Society for Paediatric Infectious Diseases congress in Lisbon, Portugal. Invasive meningococcal disease (IMD) is an uncommon but serious illness that can cause life-threatening complications or even […]


Clinical Trials, Research and Development

FDA issues new draft guidance on decentralised clinical trials

May 4, 2023

Via: PMLiVE

This could include carrying out clinical tests at a local facility rather than a research medical centre, or conducting follow-up visits in the participants’ homes using telemedicine. The 16-page document provides recommendations for sponsors, investigators and other stakeholders on the […]


Clinical Trials, Research and Development

Flatiron, Sanofi Partner on Efficiency in Clinical Trials

May 1, 2023

Via: Contract Pharma

Flatiron Health is collaborating with Sanofi to redesign the clinical trial experience for sponsors, sites, and patients in the therapeutic area of oncology. The multi-study collaboration will focus on improving clinical trial data acquisition, delivery, and quality through site-facing technology […]


Clinical Trials, Research and Development

Clinical trial begins using CAR T cells to potentially cure HIV

April 20, 2023

Via: World Pharma News

UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CAR T-cell therapy. The novel study uses immunotherapy. It involves taking a patient’s own white blood cells, called […]


Clinical Trials, Research and Development

Patient-centered clinical trials improve recruitment and retention

April 17, 2023

Via: Biopharma Dive

Patient enrollment in clinical trials is time-intensive and costly. In 2015-2016, the average cost to recruit one patient1 to a clinical study was $6,500+ and the average cost to recruit a new patient to replace a lost one was $19,000+. […]


Cell and Gene Therapy, Clinical Trials, Industry, Research and Development

Changing cell & gene therapy landscape and implications on clinical trials

April 3, 2023

Via: Biopharma Dive

Cell and gene therapy clinical research is a field that holds promise for the treatment of many diseases. These therapies involve using living cells or genes to treat or prevent diseases and have the potential to revolutionize how we approach […]


Clinical Trials, Research and Development

Monthly Injections Might Lower Bleeding in People With Hemophilia

March 31, 2023

Via: Drugs.com

An experimental injectable drug appears effective in reducing bleeds in patients with hemophilia A and B, according to a pair of new clinical trials. Two-thirds of people with treatment-resistant hemophilia who were treated with the drug fitusiran had no bleeds […]


Clinical Trials, Research and Development

Viking joins obesity drug development race with early study data

March 28, 2023

Via: Biopharma Dive

Novo Nordisk pioneered the use of insulin-stimulating diabetes drugs as weight loss treatments when it launched a high-dose version of its daily shot Victoza as Saxenda in 2014. It followed on that success years later with a weekly shot, marketed […]


Clinical Trials, Industry, Research and Development, Vaccines

BioNTech Revenues Slide with Waning Demand for COVID-19 Vaccines

March 27, 2023

Via: Contract Pharma

4Q Revenues: €4.3 billion (-23%) 4Q Earnings: €2.3 billion (-28%) YTD Revenues: €17.3 billion (-9%) YTD Earnings: €9.3 billion (-8%) Comments: Results in the quarter and FY reflect lower demand for COVID-19 vaccines. Approximately 2 billion doses of COMIRNATY invoiced […]


Clinical Trials, Research and Development

Syneos Health Partners with Microsoft to Optimize Clinical Trials

March 21, 2023

Via: Contract Pharma

Syneos Health has entered a multi-year strategic agreement with Microsoft. Using Microsoft Azure services, Syneos Health has developed an advanced analytics platform designed to enable agile deployment of machine learning (ML) supporting the analysis, design and execution of clinical trials […]


Clinical Trials, Mergers and Acquisitions, Research and Development

LEO Pharma, ICON Partner to Advance Clinical Trials in Dermatology

March 10, 2023

Via: Contract Pharma

LEO Pharma, a global leader in medical dermatology, and ICON plc, entered into a strategic partnership that will enable LEO Pharma to scale clinical trial execution that is patient-centric and cost effective, to support the company’s clinical portfolio. The partnership […]


Clinical Trials, Research and Development

BridgeBio shares jump on dwarfism drug data

March 6, 2023

Via: Biopharma Dive

Based on the latest data, BridgeBio has started enrolling children in a Phase 3 trial of infigratinib in achondroplasia and also plans to develop the medicine for patients with a closely related skeletal abnormality known as hypochondroplasia. The company has […]


Clinical Trials, Research and Development

Despite study setback, a biotech plans to push tremor drug into late-stage testing

March 3, 2023

Via: Biopharma Dive

In spite of a setback, Praxis Precision Medicines, a Boston-based biotechnology company, plans to move its most advanced experimental drug into late-stage human testing. On Friday, Praxis said its drug, named ulixacaltamide, failed to meet the main goal of a […]


Clinical Trials, Research and Development

Frequency to cut jobs after clinical trial setback

February 13, 2023

Via: Biopharma Dive

A spinout of the Massachusetts Institute of Technology, Frequency sought to develop treatments for hearing loss by regenerating lost hair cells in the inner ear, rather than turning to hearing aids or implants. Both its lead drug FX-322 and FX-345, […]


Clinical Trials, Research and Development

Clinical Trial Diversity Continues to Face Challenges

February 13, 2023

Via: Biopharm International

Policymakers and biopharma companies acknowledge the importance of assessing drugs and medical products on a wide range of ethnic and racial populations to fully understand medical effects on patients. This has bolstered support for studies to enroll patients in proportion […]


Clinical Trials, Research and Development

GSK announces results from 17-year retrospective study on US clinical trial diversity

February 9, 2023

Via: World Pharma News

GSK plc (LSE/NYSE: GSK) announced results from a retrospective study on clinical trial diversity, investigating the historical representation of US-based participants in GSK clinical trials. The study looked at clinical trial demographic data from 495 GSK and ViiV clinical trials […]


Clinical Trials, Mergers and Acquisitions, Research and Development

Cambridge Cognition and Aardex collaborate to boost decentralised clinical trials

February 3, 2023

Via: Pharma Times

Aardex Group – a company focused on remote research and healthcare adherence – and Cambridge Cognition have firmed a partnership up to provide monitoring during hybrid and decentralised clinical trials (DCTs). The link-up will involve the incorporation of Aardex’s MEMS […]


Clinical Trials, Industry, Research and Development, Vaccines

Transforming the way cancer vaccines are designed and made

February 3, 2023

Via: World Pharma News

A new way to significantly increase the potency of almost any vaccine has been developed by researchers from the International Institute for Nanotechnology (IIN) at Northwestern University. The scientists used chemistry and nanotechnology to change the structural location of adjuvants […]