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Category: Clinical Trials


Clinical Trials, News, Research and Development

Researchers Expose Hidden Atomic Portrait of Antioxidant Enzyme

April 7, 2021

Via: Genetic Engineering and Biotechnology News

Oxidative stress is caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and cells . Manganese superoxide dismutase (MnSOD) is an antioxidant enzyme that protects the mitochondria from oxidative damage by using a mechanism […]


Clinical Trials, News, Research and Development

Study identifies possible COVID-19 drugs — including several that are FDA-approved

April 2, 2021

Via: ScienceDaily

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases. […]


Clinical Trials, FDA, Regulations, Research and Development

FDA green light for BMS, bluebird bio’s CAR-T therapy Abecma in multiple myeloma

March 30, 2021

Via: Pharma Times

Abecma (idecabtagene vicleucel; ide-cel) has been cleared for use in adult patients with relapsed or refractory multiple myeloma, after four or more prior lines of therapy, including an immunomodulatory agent, a proteasome inhibitor and an anti-CD38 monoclonal antibody. In the […]


Clinical Trials, News, Research and Development

Clinical Trial Management System Market: Software is anticipated to be Most Lucrative Segment

March 30, 2021

Via: BioSpace

According to Transparency Market Research’s latest report on the global clinical trials management system (CTMS)market for the historical period 2017–2018 and forecast period 2019–2027, rising demand for new therapies and increasing research and developmental activities to drive the global clinical […]


Clinical Trials, Research and Development

Report urges pharma companies to utilise synthetic data in clinical trials

March 24, 2021

Via: Pharma Times

Synthetic data is based on real-world data sets, used to accurately predict the ‘synthetic patient profile’ and deploy a virtual cohort in a clinical trial. The report is the first in a series exploring the use of synthetic data in […]


Cell and Gene Therapy, Clinical Trials, Industry, Research and Development

Novel cancer-fighting gene therapy enters phase I clinical trial

March 18, 2021

Via: Medical News

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells. The safety of the novel therapy is now being tested on […]


Biotech, Clinical Trials, Industry, Research and Development

A first-of-its-kind mRNA drug falls short in cystic fibrosis

March 18, 2021

Via: Biopharma Dive

Messenger RNA technology, which uses synthetic, genetic material to teach the body to make helpful proteins, has come of age over the past year. When the coronavirus pandemic took hold in 2020, the technology was uniquely suited to meet the […]


Clinical Trials, Industry, Research and Development, Vaccines

Tonix Pharmaceuticals Reports Positive COVID-19 Vaccine Efficacy Results in Non-Human Primates Vaccinated with TNX-1800 and Challenged with Live SARS-CoV-2

March 17, 2021

Via: BioSpace

Tonix Pharmaceuticals, Inc.. (Nasdaq: TNXP) (Tonix or the Company), a clinical-stage biopharmaceutical company, today announced preliminary results following vaccination of non-human primates with TNX-1800 (modified horsepox virus, live vaccine), a live attenuated COVID-19 vaccine candidate engineered to express the SARS-CoV-2 […]


Clinical Trials, Industry, Research and Development, Vaccines

Modified COVID-19 vaccines can avoid ‘lengthy’ clinical studies, says MHRA

March 5, 2021

Via: Pharma Times

The new guidance, published by the MHRA alongside international regulatory authorities from Australia, Canada, Singapore and Switzerland, details what information is required to approve modifications to authorised COVID-19 vaccines. Although ‘time-consuming’ clinical studies won’t be needed, vaccine makers will need […]


Clinical Trials, Research and Development

Study of Human Brain Images Generates New Insights into the Neurobiology of the Placebo Effect

March 3, 2021

Via: Genetic Engineering and Biotechnology News

Scientists for the Placebo Neuroimaging Consortium have undertaken a systematic meta-analysis of human neuroimaging studies to generate new insights into how placebo treatments for pain reduction—placebo analgesia—reduce pain-related activity in multiple areas of the brain. The team claims their research, […]


Clinical Trials, Research and Development

Phage Therapy Successful in Mice, but Resistance Looms

February 24, 2021

Via: Genetic Engineering and Biotechnology News

Since just before the turn of the 20th century, bacteriophage’s antibacterial activity was detected in the waters of the Ganges and Yamuna rivers. English bacteriologist Ernest Hankin had written about the bactericidal effect against cholera of something in the filtered […]


Clinical Trials, Research and Development

Cellular Health Maintenance System Degradation May Lead to Advanced Huntington’s

February 24, 2021

Via: Genetic Engineering and Biotechnology News

Using a computational approach to analyze large brain cell gene expression datasets, researchers at MIT and Sorbonne Université say they have found that Huntington’s disease may progress to advanced stages more because of a degradation of the cells’ health maintenance […]