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Category: Clinical Trials


Clinical Trials, Research and Development

Pharmacy chain Walgreens plans to disrupt clinical trial sector

June 17, 2022

Via: Pharmaphorum

The company says it plans to use a “flexible” model, drawing on both decentralised trial (DCT) and conventional site-based models via its Health Corner and Village Medical outlets at various Walgreens locations across the US. The move follows in the […]


Clinical Trials, Research and Development

Another amyloid miss in Alzheimer’s as Roche’s crenezumab fails trial

June 16, 2022

Via: Pharmaphorum

The result isn’t a big surprise – Roche terminated two phase 3 trials of crenezumab in people with prodromal to mild sporadic Alzheimer’s in early 2019 after interim analyses found it would be futile to continue – but is another […]


Clinical Trials, Research and Development

FDA’s treatment of China-developed drugs spurs demands for multiregional clinical trials

June 14, 2022

Via: Pharmaphorum

China’s emergence as an R&D powerhouse means that the country is quickly adding a number of drug candidates to the global pipeline. Despite more treatment options being a positive, Ben Hargreaves finds that this has raised issues over single-region clinical […]


Clinical Trials, Research and Development

FDA puts Sanofi’s Cialis prescription-to-OTC trial on hold, citing problems with study’s design

June 1, 2022

Via: FiercePharma

Sanofi’s effort to switch erectile dysfunction pill Cialis to over-the-counter (OTC) availability from its original prescription status has been slowed to a grinding halt with the FDA’s decision to put a trial on hold. The FDA halted an “actual use […]


Clinical Trials, Research and Development

Moleculin Commences Dosing in Healthy Volunteers in Phase 1a Clinical Trial of WP1122 for the Treatment of COVID-19

May 26, 2022

Via: Drugs.com

Moleculin Biotech, Inc., (“Moleculin” or the “Company”), a clinical stage pharmaceutical company with a broad portfolio of drug candidates targeting highly resistant tumors and viruses, today announced the commencement of dosing in its first-in-human Phase 1a study to evaluate the […]


Clinical Trials, Research and Development

FDA lifts hold on Ocugen’s COVID-19 vaccine trial. But is it too late for the shot?

May 23, 2022

Via: FiercePharma

Six weeks after slapping a clinical hold on a trial of Ocugen’s COVID-19 vaccine, the FDA has lifted it. That’s the good news for the Malvern, Pa. company, which has partnered with India’s Bharat Biotech on the shot known commercially […]


Clinical Trials, Research and Development

Death triggers FDA hold on Foghorn blood cancer clinical trial, shrouding timing of data drop

May 20, 2022

Via: FierceBiotech

The FDA has sounded a warning about Foghorn Therapeutics’ blood cancer candidate FHD-286, putting a phase 1 clinical trial on a partial hold in response to the death of a patient with potential differentiation syndrome. FHD-286 is an enzymatic inhibitor […]


Clinical Trials, Research and Development

Oncomatryx announces 15m euros funding to conduct clinical trials

April 20, 2022

Via: Pharma Times

Company at the forefront of developing personalised treatments against invasive cancer has raised 15m euros to conduct clinical trials Oncomatryx has announced the beginning of a new phase in the development of its tumour microenvironment – targeted antibody drug conjugates […]


Clinical Trials, Research and Development

ISA Pharmaceuticals announce new trial testing technology for cancers

April 14, 2022

Via: Pharma Times

A clinical trial of Amplivant – an adjuvant technology to boost immune response to cancer therapy –has started. ISA Pharmaceuticals’ novel technology is being tested in a multicentre clinical trial which is also testing the Moditop vaccine, Modi-1. The first-in-human […]


Clinical Trials, Research and Development

FDA puts Curis’ leukemia trial on partial hold after patient death spurs review of muscle breakdown

April 4, 2022

Via: FierceBiotech

The list of biotechs under clinical hold keeps getting longer. Curis is the latest company to join the list, with the FDA slapping a partial hold on a phase 1/2a leukemia study while it gathers information about the death of […]


Clinical Trials, Research and Development

Potential Strategy Halts Cancer’s Key Cell Repair Mechanism

April 1, 2022

Via: Genetic Engineering and Biotechnology News

Researchers are actively searching for ways to extend the survival benefit of targeted cancer therapies to prevent the possibility of highly resistant tumors. A new study led by researchers at the Duke Cancer Institute describes a potential new strategy to […]


Clinical Trials, FDA, Regulations, Research and Development

FDA Advisory Panel Narrowly Votes Against New ALS Drug

March 31, 2022

Via: Drugs.com

In a close vote, an advisory panel for the U.S. Food and Drug Administration decided not to recommend the approval of an experimental drug for the deadly neurological disease amyotrophic lateral sclerosis (ALS). The panel’s decision had been closely watched, […]