Clinical Trials, Research and Development
March 12, 2024
Via: Biopharma DiveFor Rick Bedlack, director of the ALS clinic at Duke University, tough times come with the job. He and his team treat about 500 people with the rare, fatal disorder that rapidly erodes nerve cells. Friday, though, was particularly difficult. […]
Clinical Trials, Research and Development
March 11, 2024
Via: Drugs.comFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market. In a statement issued Friday, Amylyx Pharmaceuticals said that Relyvrio failed to help patients in a large follow-up study, but the company […]
Cell and Gene Therapy, Clinical Trials, Industry, Research and Development
March 6, 2024
Via: PMLiVEAffecting an estimated one in 10,000 infants globally, SMA is a rare, genetic neuromuscular disease and a leading genetic cause of infant death. Caused by the lack of a functional SMN1 gene, the most severe forms of SMA result in […]
Clinical Trials, Research and Development
March 5, 2024
Via: Biopharma DiveThe study results represent the first human data from Apogee, which last year became one of the rare preclinical biopharmaceutical companies to succeed in a tough market for initial public offerings. After launching in late 2022, Apogee raised $300 million […]
Clinical Trials, Research and Development
February 20, 2024
Via: Biopharma DiveAnalysts have followed Rapt as they view its drug, an oral pill dubbed zelnecirnon, as a possible competitor to Dupixent in conditions like eczema. Dupixent, which was developed by Sanofi and Regeneron, is a multibillion-dollar product approved for a range […]
Clinical Trials, Research and Development
February 20, 2024
Via: Pharma TimesInnovative Trials has announced a new initiative designed to boost clinical trial patient retention in paediatric studies, in partnership with the Oliver Patch Project, a US charity. The Retention Patch Program is designed to engage directly with children and young […]
Clinical Trials, Research and Development
January 23, 2024
Via: PharmaphorumTesting a person’s blood for a protein called phosphorylated tau could provide a means of large-scale screening for Alzheimer’s disease (AD), according to a new study. The immunoassay – which has been developed by California biotech ALZpath – focuses on […]
Clinical Trials, Research and Development
December 28, 2023
Via: PharmaphorumTreatment with the cardiac myosin inhibitor significantly improved exercise capacity in patients with obstructive hypertrophic cardiomyopathy (HCM), an inherited disorder in which the heart muscle becomes thickened and can obstruct blood flow. It is one of the most common reasons […]
Clinical Trials, Research and Development
December 4, 2023
Via: Biopharma DiveWith clinical trials becoming more complex, finding ways to streamline and automate laboratory processes is vital when analyzing bioanalytical samples. As the chief scientific officer of large-molecule bioanalysis, Dr. Tom Zhang leverages his expertise to promote ever-evolving automation technologies. He […]
Clinical Trials, Research and Development
November 21, 2023
Via: PMLiVEEvinova will aim to better meet the needs of healthcare professionals, regulators and patients. The new healthtech business aims to bring to market established and scaled digital technology solutions which are already used globally by AZ, to pharmaceutical, biotechnology and […]
Clinical Trials, Research and Development
November 15, 2023
Via: PharmaphorumThe two companies say their partnership could unlock access to millions of customers across a network of more than 550 Chemist Warehouse retail locations in Australia and other countries including New Zealand, Ireland and China, as well as its online […]
Clinical Trials, Research and Development
November 13, 2023
Via: Biopharma DivePandemic-era changes may have permanently altered the clinical trial landscape as decentralized clinical trials gain broader acceptance. During COVID-19, more than three-quarters (76%) of pharmaceutical companies, device manufacturers and contract research organizations conducted off-site clinical trials. These types of trials […]
Clinical Trials, Research and Development
October 16, 2023
Via: Biopharma DivePharmaceutical companies can spend 10 to 15 years and more than $2.3 billion to bring new drugs to market. Despite these significant investments in drug development, 90% of clinical trials fail. For a greater chance of success, pharmaceutical companies must […]
Clinical Trials, Research and Development
October 12, 2023
Via: PharmaphorumThe notification scheme stems from the agency’s overhaul of rules announced in March, with the aim of making it “faster and easier” to gain approval and to run clinical trials in the UK – and elevate the country’s position in […]
Clinical Trials, Industry, Pharma, Research and Development
September 1, 2023
Via: Biopharm InternationalClinical trials are essential for establishing the efficacy of new drugs, observing patients’ reactions to treatments, and representing populations of people that may not always be discussed in everyday conversation. Although there are many diseases and disorders that are waiting […]
Clinical Trials, Research and Development
August 21, 2023
Via: Biopharm InternationalOn Aug. 21, 2023, Gilead Sciences announced that FDA has placed a partial clinical hold on the company initiating new patients into US studies for magrolimab, an investigational anti-CD47 immunotherapy, to treat acute myeloid leukemia (AML). FDA’s decision follows a […]
Clinical Trials, Research and Development
August 7, 2023
Via: Biopharma DiveAlthough diseases such as Ehlers-Danlos syndrome, Sanfilippo syndrome and Hemophilia are considered rare, their impact looms large. Rare diseases, defined as occurring in fewer than one in 2,000 individuals, affect more than 300 million people across the globe, and most […]
Clinical Trials, Research and Development
July 26, 2023
Via: PMLiVEThe report presents EU-level actions to address the challenges that were experienced during the COVID-19 pandemic and the outbreak of mpox disease in setting up adequately sized clinical trials across multiple member states. Organised in June 2023, with participation from […]
Clinical Trials, Research and Development
July 17, 2023
Via: Biopharma DiveAn experimental medicine benefited patients with a deadly heart condition in a closely watched Phase 3 trial, lifting the fortunes of its developer, BridgeBio Pharma, and clearing the way for the biotechnology company to seek U.S. approval. Trial results showed […]
Clinical Trials, Research and Development
July 14, 2023
Via: Pharma TimesCaribou Biosciences – a company focused on genome-editing – has announced follow-up data from the dose escalation element of its ongoing ANTLER phase 1 trial. This new data set includes all 16 patients treated in dose escalation with the CB-010 […]