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Category: News


News

Genentech withdraws US indication of Tecentriq for bladder, urinary tract cancer

November 30, 2022

Via: Pharmaphorum

Following a consultation with the US Food and Drug Administration (FDA), and in accordance with the requirements of the FDA’s Accelerated Approval Program, Genentech has chosen to withdraw the US indication of atezolizumab for the treatment of adults with locally […]


News

Chronic Wounds Heal Quicker with Smart Bandages

November 29, 2022

Via: GEN

Scientists at Stanford University say they have developed a wireless smart bandage that has shown promise in speeding up tissue repair by monitoring the wound healing process and treating the wound simultaneously. The study “Wireless, closed-loop, smart bandage with integrated […]


News

Genomic testing ‘should be offered to all cancer patients in Scotland’

November 28, 2022

Via: Pharmaphorum

The Scottish Precision Medicines Industry Group (SPMIG) – set up by AstraZeneca, Lilly, Novartis and Roche – is calling on NHS Scotland to make genomic testing available for every cancer patient in the country, so they can receive drugs based […]


News

FogPharma clears another big-ticket financing for its ‘miniprotein’ pipeline

November 22, 2022

Via: Pharmaphorum

The Series D comes a little over 18 months after the six-year-old biotech’s third-round financing netted it around $107 million, taking its total raised to date north of $360 million. Ut comes just as FogPharma is preparing to start clinical […]


News

Delivering RNA Therapeutics through Silicon Stabilized Hybrid Lipid Nanoparticles

November 21, 2022

Via: GEN

Recent advances in biotechnology and genetic engineering have produced new therapeutics and treatment modalities for many diseases and created an emphasis on effectively delivering novel drugs to their target destinations. RNA-based therapeutics are poised to revolutionize treatment options for a […]


News

Roche’s high-throughput monkeypox test approved for emergency use by FDA

November 17, 2022

Via: PMLiVE

The real-time polymerase chain reaction (PCR) test will detect DNA from MPXV in lesion swabs collected from individuals suspected of infection by their healthcare provider. The tests will be conducted on Roche’s 6800/8800 cobas systems, which can also detect HIV, […]


News

Acrivon cuts IPO price to raise $99M for plan to revive old Lilly cancer drug

November 15, 2022

Via: Biopharma Dive

Like a number of the other biotech startups to reach Wall Street this year, Acrivon is primarily focused on a single drug and getting it to market. Its lead drug is prexasertib, a small molecule targeting a pair of enzymes […]


News

Dupixent nears EU approval for rare skin disease prurigo nodularis

November 14, 2022

Via: Pharmaphorum

The EMA’s human medicines committee (CHMP) has recommended IL-4 and IL-13 inhibitor Dupixent (dupilumab) to treat adults with moderate to severe PN, a disease which causes hard lumps to form on the skin that are so itchy they can lead […]


News

Alzheimer’s treatment hopes take another dive as Roche drug fails trial

November 14, 2022

Via: Pharmaphorum

The failure is entirely in line with the overall trend in assessments of Alzheimer’s drugs that target amyloid beta – the protein that forms deposits in the brain tissue of patients with the disease – which have resulted in dozens […]


News

NRG announces £16m Series A for IND for Parkinson’s and ALS

November 9, 2022

Via: Pharmaphorum

A pre-clinical pipeline of potential first-in-class brain-penetrant small molecule inhibitors of the mitochondrial permeability pore (mPTP) are to be developed. These will act through a novel mechanism of action and be used in treatment of Parkinson’s and Amyotrophic Lateral Sclerosis […]


News

Artificial Intelligence for better antibody drugs: ready for prime time?

November 7, 2022

Via: Pharmaphorum

Artificial Intelligence (AI) and deep learning have already transformed several aspects of small molecule drug design. Recent advances in the area are now also impacting more complex tasks, such as design and optimisation of antibodies. As a result, 2022 saw […]


News

Mining (and Refining) the Stuff of Gene Editing Tools

November 4, 2022

Via: GEN

The gene editing world has been revolutionized by the Nobel Prize–winning CRISPR-Cas9 system. Although CRISPR-Cas9 offers advantages over earlier genome editing methods, it isn’t necessarily the last word. Indeed, the past decade has revealed limitations of CRISPR-Cas9, which can’t tackle […]


News

Benefits of PCR-Based Molecular Diagnostics

November 3, 2022

Via: GEN

In vitro diagnostics (IVD) is an umbrella term for tests conducted on blood or tissue samples to detect diseases, determine the efficacy of novel or established treatments, and monitor health. Emerging precision medicine approaches use IVDs to identify patients who […]


News

Alnylam scraps trial in rare eye disorder, blaming drug price reforms

October 28, 2022

Via: Pharmaphorum

The IRA was signed by Biden in August and introduced a framework that will require Medicare, the US’s government-run insurance programme for older Americans, to negotiate with manufacturers a “reasonable” price for selected brand name drugs on the basis of […]


News

It’s been a long time coming for long-term topical psoriasis treatments

October 26, 2022

Via: Pharmaphorum

Topicals — creams, ointments, foams, and lotions applied directly to the affected areas of the skin — don’t get nearly as much TV time as their systemic biologic counterparts, the self-injectables with catchy theme songs, where the smiley and sleeveless […]


News

Fully Mature Hair Follicles Generated in the Lab as Cultured “Follicloids”

October 25, 2022

Via: GEN

A team of researchers from Japan studying the processes of hair follicle growth and hair pigmentation has successfully generated hair follicles in cultures, by controlling epithelial-mesenchymal interactions (EMI), and the arrangement of epithelial and mesenchymal cells in three dimensions, in […]


News

The power of self-management to target gaps in chronic disease care

October 25, 2022

Via: Pharmaphorum

Healthcare systems are currently going through a period of reflection on how to serve the needs of the greatest range of patients possible. This is an ongoing challenge, and one that reared its head again during the pandemic, as questions […]


News

Enhanced Genome Editing Toolkit Focuses on Delivery and Precision

October 24, 2022

Via: GEN

It is no surprise that technical progress in altering genes precisely, permanently, and safely is driving advances in biotechnology research. Genome editing is the key to delivering on the promise of the human genome project (HGP). Once scientists deduce relationships […]


News

IPO Raises $175M for Prime, Developer of “Search and Replace” Gene Editing Platform

October 21, 2022

Via: GEN

Prime Medicine, the developer of a “search and replace” gene editing platform, has launched an upsized initial public offering (IPO) that raised $175 million in gross proceeds—about $24 million more than projected just last week. Prime finished its first day […]


News

Nucleome raises £37.5m to shine light on ‘dark genome’

October 19, 2022

Via: Pharmaphorum

The dark genome – a loose term that covers non-coding regions of the genome that are capable of regulating the expression of genes, previously rather inaccurately referred to as junk DNA – is increasingly being explored by biopharma companies for […]