Category: Vaccines

September 22, 2022

Alexandre Le Vert, CEO and co-founder of Osivax, discusses the company’s breakthrough vaccine technology, oligoDOM, and how it’s driving the development of new influenza and SARS-CoV-2 vaccines that attack T-cells, providing a long-lasting effect. Currently, available vaccines for influenza and […]

September 20, 2022

Vaccines have transitioned from being a largely unloved area of the industry, with multiple big pharma companies divesting their vaccine divisions, to the biggest revenue drivers seen in recent years. This all comes down to the impact of the pandemic. […]

September 15, 2022

The first patients have been dosed in a phase 3 trial of an mRNA-based seasonal influenza vaccine developed by Pfizer and BioNTech, which may offer quicker production and greater efficacy than shots made using traditional cell culture or recombinant techniques. […]

September 15, 2022

An experimental meningococcal vaccine that protects against five strains of the bacteria succeeded in a Phase 3 clinical trial, Pfizer said Thursday, potentially offering an alternative to existing shots that cover fewer variants and require more doses. By the end […]

September 12, 2022

The European Commission is now expecting to make a final decision on the updated version of the two drugmakers’ original Comirnaty shot within the next couple of weeks. The EMA said the decision by the CHMP will “further extend the […]

September 8, 2022

Hopes were already running high for the R21/Matrix-M vaccine, after it showed 77% protective efficacy over 12 months in a phase 2b trial involving young west African children – meeting the World Health Organization’s efficacy goal of 75% – after […]

September 7, 2022

While researchers explore the possibilities of COVID-19 vaccines that don’t require an injection, public health officials in India and China have already each approved new needle-free versions for their citizens. In India, regulators on Tuesday approved a nasal vaccine developed […]

September 7, 2022

COVID-19 vaccines will likely go the way of flu shots in the future, with updated doses given annually, U.S. health officials said Tuesday. “In the absence of a dramatically different variant, we likely are moving towards a path with a […]

September 6, 2022

The NHS is moving to the next phase of its SARS-CoV-2 vaccination programme, following health secretary Steve Barclay’s acceptance of advice from the Joint Committee on Vaccination and Immunisation (JCVI) to go ahead with rollout of Pfizer’s bivalent 30mg booster […]

September 2, 2022

The EMA’s human medicines committee (CHMP) has recommended authorisation of two COVID-19 vaccines from Moderna and Pfizer/BioNTech that include sequences coding for Omicron spike protein as booster shots. The European Commission said it will move ahead with an accelerated authorisation […]

August 31, 2022

The Food and Drug Administration has authorized updated COVID-19 booster vaccines for emergency use, hoping the reformulated shots from partners Pfizer and BioNTech and Moderna can curb an expected wave of new infections this winter. The FDA on Wednesday cleared […]

August 30, 2022

COVID-19 vaccines do not increase your risk for stroke, new research shows, but severe COVID infection does, and experts hope the finding will ease the concerns of those who are hesitant to get the shot. “We now know that patients […]

August 26, 2022

Moderna has filed complaints in the US and Germany claiming that the mRNA technology used to make Pfizer and BioNTech’s Comirnaty vaccine infringes multiple patents that cover its own Spikevax shot. Among the claims is that Comirnaty was developed using […]

August 25, 2022

Today on the pharmaphorum podcast, Editor in Chief Jonah Comstock welcomes Hedi Ben Brahim and Eric Quéméneur, CEO and chief science officer respectively of Transgene, to discuss cancer vaccines in general and Transgene’s recent work in the space in particular. […]

August 23, 2022

The key ingredient in the coronavirus vaccines developed by Moderna and BioNTech doesn’t last very long. Once in the body, this messenger RNA, or mRNA, degrades within days. Still, that’s enough time for the vaccines to train the body to […]

August 23, 2022

The new version of their Comirnaty vaccine includes mRNA for the spike protein of the wild-type SARS-CoV-2 that first emerged in late 2019, as well as for the BA.4 and BA.5 subvariants of the now-dominant Omicron variant. It will also […]

August 22, 2022

The recommendation comes after a review of a clinical trial which found that delivering a smaller dose intradermally – just below the top layer of the skin – is as effective as giving the standard dose subcutaneously as recommended on […]

August 22, 2022

The company must produce the initial results of a randomised controlled trial of a second course of the antiviral by 30 September next year, according to a letter from the regulator. The order follows reports of rebounding COVID-19 symptoms after […]

August 19, 2022

Grand River Aseptic Manufacturing (GRAM), a parenteral drug product contract development and manufacturing organization (CDMO), has entered into an agreement with Bavarian Nordic, a Denmark-based vaccine company, to fill and finish JYNNEOS smallpox/monkeypox vaccine. The agreement was supported by the […]

August 17, 2022

As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially Omicron, have developed ways to evade the antibodies we make in response to vaccines. A new, broadly neutralizing […]