Clinical Trials, Mergers and Acquisitions, Research and Development
February 3, 2023
Via: Pharma TimesAardex Group – a company focused on remote research and healthcare adherence – and Cambridge Cognition have firmed a partnership up to provide monitoring during hybrid and decentralised clinical trials (DCTs). The link-up will involve the incorporation of Aardex’s MEMS […]
Clinical Trials, Industry, Research and Development, Vaccines
February 3, 2023
Via: World Pharma NewsA new way to significantly increase the potency of almost any vaccine has been developed by researchers from the International Institute for Nanotechnology (IIN) at Northwestern University. The scientists used chemistry and nanotechnology to change the structural location of adjuvants […]
Manufacturing, Research and Development
February 1, 2023
Via: Biopharm InternationalBiologics, especially protein drugs, are often produced in cultured cells. Those cultured cells, called host cells, synthesize the target proteins along with the proteins coded by the cell genome for the cells’ own survival, function, and reproduction. Purifying the target […]
Cell and Gene Therapy, Clinical Trials, Industry, Research and Development
January 31, 2023
Via: Biopharm InternationalBe The Match BioTherapies, a provider of solutions for developing and commercializing cell and gene therapies, in conjunction with the Center for International Blood and Marrow Transplant Research (CIBMTR), is offering expanded clinical research organization (CRO) services. These services are […]
Clinical Trials, Research and Development
January 26, 2023
Via: PharmaphorumMerck has said it will abandon the KEYNOTE-991 study of PD-1 inhibitor Keytruda (pembrolizumab) in patients with metastatic hormone-sensitive prostate cancer (mHSPC) after it showed no benefit on either overall survival (OS) or radiographic progression-free survival (rPFS) when the data […]
Manufacturing, Research and Development
January 24, 2023
Via: Biopharma DiveEli Lilly will invest $450 million in a North Carolina manufacturing plant to meet growing demand for its diabetes drugs Mounjaro and Trulicity, the company said Tuesday. The investment in the Research Triangle Park plant will expand filling, device assembly […]
Manufacturing, Research and Development
January 24, 2023
Via: PharmaphorumA just-published report from the Medicines Manufacturing Industry Partnership (MMIP) – set up by the UK government and biopharma industry in 2014 to drive growth in the category – says the sector has the potential to be a driver for […]
Clinical Trials, Research and Development
January 18, 2023
Via: PharmaphorumThe DNA of these so-called ‘genetic superheroes’ may contain clues about how to treat severe disease. By studying their natural resilience and using it to design new therapies, it could help so many people. However, the Resilience Project’s scientists had […]
Clinical Trials, Research and Development
January 17, 2023
Via: PharmaphorumUnify, launched in December 2020, is AstraZeneca’s patient app and clinical trial support tool. Already, it is operating at scale across the company, used in more than 28 countries and available in 62 languages. Dissecting heterogeneity To begin discussions, pharmaphorum […]
Clinical Trials, Research and Development
January 12, 2023
Via: PharmaphorumThe announcement marks the disappointing end of a marathon effort by Oramed to develop an oral insulin formulation for type 2 diabetes struggling to control blood sugar on standard therapies and as an alternative to injections. It exposes once again […]
Clinical Trials, Research and Development
January 9, 2023
Via: Biopharma DiveArrowhead’s drug, called fazirsiran, is designed to treat alpha-1 antitrypsin deficiency, a genetic condition in which a mutant form of the namesake protein accumulates in liver cells, causing fibrosis and cirrhosis. Alpha-1 antitrypsin, or AAT, deficiency has become a target […]
Manufacturing, Research and Development
January 9, 2023
Via: Contract PharmaGinkgo Bioworks, which is building a platform for cell programming and biosecurity, has opened Bioworks7, the latest expansion of its biological engineering foundry. With this new space, Ginkgo increases its capacity and capabilities to serve its partners in the spaces […]
Clinical Trials, Research and Development
January 5, 2023
Via: PharmaphorumBioethics International has developed a benchmarking tool for “fair inclusion” in clinical trials, drawing on pivotal trials submitted to the FDA in support of 59 new cancer therapeutics – submitted by 25 sponsors – that were approved by the regulator […]
Clinical Trials, Research and Development
January 4, 2023
Via: PMLiVEThe start of the trial triggers a $5m milestone payment from AZ, which licensed AZD3152 from RQ Bio in May last year, and reinforces the financial position of the UK-based biotech to execute its four scientific programmes focused on viral […]
Clinical Trials, Research and Development
January 3, 2023
Via: Biopharma DiveThe biotechnology industry begins 2023 at a crossroads. In many ways, the sector is coming off of one of its toughest years in recent memory. Initial public offerings ground to a halt. A widely followed biotech stock index plunged nearly […]
Clinical Trials, Research and Development
January 3, 2023
Via: PharmaphorumHaemophilia is a rare genetic bleeding disorder that causes the blood to take a long time to clot because of a deficiency in one or several blood clotting factors. It is almost exclusively found in males. According to the World […]
Clinical Trials, Research and Development
January 3, 2023
Via: PharmaphorumThe Hong Kong-listed cancer biotech said this morning that anti-PD-L1 inhibitor sugemalimab given in combination with chemotherapy showed “statistically significant and clinically meaningful” improvements in both progression-free survival (PFS) and overall survival (OS) in previously-untreated patients with unresectable locally advanced, […]
Clinical Trials, Research and Development
January 3, 2023
Via: PharmaphorumThe Italian biopharma said it had decided to press ahead with the new study after assessing results from 100 patients with TRS in open-label studies who received the glutamate modulator drug as an add-on to their current therapy for more […]
Clinical Trials, Research and Development
December 30, 2022
Via: PharmaphorumThese are all critical consideration for sponsors, as failing to conduct trials in accordance with GCP and other applicable regulations can lead to regulatory authorities rejecting data that is generated to support new treatments and regulatory applications, as well as […]
Clinical Trials, Research and Development
December 29, 2022
Via: Biopharma DiveDrugmakers have long studied hemophilia gene therapies, seeking to replace the infusions that people with the disease take for life to control their bleeding. In recent years, their research has delivered clinical successes in both the “A” and “B” forms […]