Category: Cell and Gene Therapy

November 20, 2020

Researchers used metal-organic frameworks (MOFs) enhanced with a green tea phytochemical coating to target human prostate cancer cells for the first time. The new method for deploying the genetic snipping tool directly into target cells is a big step towards […]

November 19, 2020

Catalent has appointed Behzad Mahdavi, Ph.D., MBA, as Vice President of Open Innovation, Biologics, Cell and Gene Therapy. In this new role, Dr. Mahdavi will join a team of experts in Catalent’s Science and Technology Group that works with customers […]

November 17, 2020

A new company has been founded to supply software for managing cell & gene therapy manufacturing. Autolomous, founded in February 2019, has already secured four different clients whom they hope to assist with digitizing and streamlining their workflows. “There’s a […]

November 16, 2020

Lemur tyrosine kinase 3 (LMTK3) is associated with cell proliferation and endocrine resistance in breast cancer. Now, a team of researchers from the University of Sussex has completed a five-year study that provides evidence for a potential new target for […]

November 12, 2020

Researchers from Penn Medicine have developed a new targeted approach that modifies viral vectors and inhibits toxicities in the sensory neurons of dorsal root ganglia (DRG) that commonly occur following the use of gene therapy for neurological diseases. This strategy […]

November 10, 2020

Talaris Chief Executive Officer Scott Requadt sees FCR001, the company’s investigational cell therapy, as a potential pipeline in a product (an experimental treatment that could have multiple uses across a number of indications). In fact, it was that versatility of […]

November 5, 2020

Scientists have used gene therapy to regenerate damaged nerve fibers in the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the leading causes of blindness worldwide. Axons – nerve fibers – in […]

November 4, 2020

Existing multiple sclerosis therapies systematically modulate the immune system to dampen its erroneous attack on the protective myelin sheaths around nerve cells, which is the hallmark of the autoimmune disease. But this approach puts patients at a higher risk of […]

November 2, 2020

Scientists at the University of Massachusetts, Amherst, have used what they claim is an unprecedented objective approach to identify which genes and molecular pathways— including mechanisms involving aging, lipid metabolism, and autoimmune disease—are most sensitive to chemical exposure. Headed by […]

October 29, 2020

Catalent has signed an agreement with Bone Therapeutics to acquire its cell therapy manufacturing subsidiary, Skeletal Cell Therapy Support SA (SCTS), including all of its assets located in Gosselies, Belgium. Catalent will purchase the shares of SCTS, currently held by […]

October 28, 2020

Bayer AG has acquired Asklepios BioPharmaceutical, Inc. (AskBio) for $2 billion upfront and potential success-based milestone payments of up to $2 billion. The U.S.-headquartered biopharma specializes in the research, development and manufacturing of gene therapies across different therapeutic areas. AskBio’s […]

October 26, 2020

A five-year-old girl with Mucopolysaccharidosis Type IIIA (MPS IIIA) has died in the Phase II/III AAVance clinical trial (NCT03612869), designed to evaluate the efficacy of Lysogene’s gene therapy candidate LYS-SAF302 in improving or stabilizing the neurodevelopmental state of MPS IIIA […]