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Mistrust in healthcare is hitting clinical trial enrolment

The analysis found that historical abuses in clinical trials and negative experiences patients may have experienced with their own medical care have generated a reluctance – particularly among communities with lower socioeconomic status – to participate in studies.

One example of that is the Tuskegee experiments in the 1930s, which exploited African American men to explore the consequences of untreated syphilis, even though an effective treatment (penicillin) was available at the time. Those experiments have “left a legacy of scepticism and reluctance to participate in clinical trial research,” according to Trinity Life Sciences, which carried out the survey.

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