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Tag: featured


Cell and Gene Therapy, Industry, Mergers and Acquisitions

AstraZeneca Acquires Neogene, Expanding in Cancer Cell Therapy

November 30, 2022

Via: GEN

AstraZeneca has agreed to acquire Neogene Therapeutics for up to $320 million cash, the companies said Tuesday, in a deal intended to bolster the buyer’s portfolio of cancer-fighting cell therapies. Neogene specializes in discovering, developing, and manufacturing next-generation T-cell receptor […]


News

Chronic Wounds Heal Quicker with Smart Bandages

November 29, 2022

Via: GEN

Scientists at Stanford University say they have developed a wireless smart bandage that has shown promise in speeding up tissue repair by monitoring the wound healing process and treating the wound simultaneously. The study “Wireless, closed-loop, smart bandage with integrated […]


Industry, Vaccines

mRNA Vaccine Provides Broad Protection against All Known Influenza Subtypes

November 29, 2022

Via: GEN

Researchers at the Perelman School of Medicine at the University of Pennsylvania have developed an experimental multivalent mRNA-based vaccine against all 20 known subtypes of influenza virus. Their approach differs from previous attempts to craft a universal flu vaccine, by […]


Clinical Trials, Research and Development

COVID in Pregnancy Can Vary — Get Vaccinated to Stay Safe

November 28, 2022

Via: Drugs.com

When pregnant women contract COVID-19, one in 10 will have moderate, severe or even critical symptoms, a new study finds. So it’s important they get their COVID vaccines, experts say. “Given that patients in all trimesters of pregnancy are susceptible […]


Industry, Pharma

How automation can help to address supply chain challenges in pharma

November 28, 2022

Via: Pharmaphorum

Empowering labs with automated equipment that produces rich, traceable, and actionable data insights means pharmaceutical companies can ensure drug production runs smoothly – even under stress. Modular set ups, remote monitoring systems, and automated batch processing can all assist in […]


Industry, Pharma

Why should pharma invest in digital products for those living with rare diseases?

November 23, 2022

Via: Pharmaphorum

Many will also face barriers to care, where access to specialists is limited and often geographically out of reach. That’s where technology coupled with user-centred design can help – bringing solutions and convenience to these pain points and positively impacting […]


News

FogPharma clears another big-ticket financing for its ‘miniprotein’ pipeline

November 22, 2022

Via: Pharmaphorum

The Series D comes a little over 18 months after the six-year-old biotech’s third-round financing netted it around $107 million, taking its total raised to date north of $360 million. Ut comes just as FogPharma is preparing to start clinical […]


Clinical Trials, Research and Development

Gut Microbiome Drives Production of Neutrophils after Prolonged Chemotherapy

November 22, 2022

Via: GEN

The results of a study by researchers at Hokkaido University’s Faculty of Medicine have shown how composition of the gut microbiome is crucial to driving a process known as granulopoiesis that replenishes neutrophil counts in the blood of mice following […]


Pricing, Regulations

Provention prices type 1 diabetes drug Tzield at $194,000

November 21, 2022

Via: Pharmaphorum

The company argues that the cost is justified as Tzield (teplizumab) is the first drug that can delay the onset of type 1 diabetes, fending off the time when they become highly reliant on insulins and at risk of the […]


News

Delivering RNA Therapeutics through Silicon Stabilized Hybrid Lipid Nanoparticles

November 21, 2022

Via: GEN

Recent advances in biotechnology and genetic engineering have produced new therapeutics and treatment modalities for many diseases and created an emphasis on effectively delivering novel drugs to their target destinations. RNA-based therapeutics are poised to revolutionize treatment options for a […]


Clinical Trials, Industry, Research and Development, Vaccines

Kids Born by C-Section May Have Weaker Response to Vaccines

November 16, 2022

Via: Drugs.com

Babies born via cesarean section may not mount as strong an immune response after some childhood vaccines compared to babies delivered vaginally, researchers suggest. Antibody levels can be checked in blood or saliva, and babies born vaginally had higher levels […]


Biotech, Industry

After $250M Roche buyout, a startup plans a second strike with fresh funding

November 15, 2022

Via: Biopharma Dive

Two months ago, biotechnology startup Good Therapeutics struck it big. A cancer immunotherapy the company was working on drew such interest from Roche that the Swiss pharmaceutical giant paid $250 million, far more than the $30 million the startup had […]


Clinical Trials, Research and Development

Propelling clinical research into the 21st century

November 15, 2022

Via: Pharmaphorum

Thankfully, the world has mostly returned to normal and the virus will hopefully be a thing of the past in the near future. The pandemic leaves myriad economic, social, health, and psychological scars in its wake. It caused intense suffering […]


Clinical Trials, Industry, Research and Development, Vaccines

Sanofi/GSK’s next-generation COVID-19 booster granted EC approval

November 14, 2022

Via: PMLiVE

Shipments of the Beta-targeting booster are ready to be distributed to European countries as per advance purchase agreements, the companies said in a statement, in time for autumn/winter COVID-19 vaccination campaigns. “Today’s approval validates our research in developing a novel […]


Clinical Trials, Research and Development

Lindis biotech presents encouraging data from bladder cancer trial

November 14, 2022

Via: Pharma Times

Lindis Biotech has announced positive data from all three dose groups from its ongoing Catunibla phase 1 trial. The objective of developing the drug candidate is to reduce the rate of radical bladder removal – also known as cystectomy – […]


Mergers and Acquisitions

Sanofi signs $1.2bn research alliance with AI specialist Insilico

November 9, 2022

Via: Pharmaphorum

The alliance is backloaded, with $21.5 million paid upfront and Insilico also in line for mid-single to up to low double-digit tiered royalties for any products developed, but it is comfortably the Chinese company’s largest deal to date. “This collaboration […]


Clinical Trials, Research and Development

Melanoma Patient Subset May Not Face Same Risks Traditionally Associated with the Disease

November 8, 2022

Via: GEN

Scientists using cancer registry data identified a subset of patients with early-stage melanoma with almost no melanoma-related deaths. The study “Prognostic modeling of cutaneous melanoma stage I patients using cancer registry data identifies subsets with very low melanoma mortality,” published […]


Clinical Trials, Research and Development

Diabetic Insulin Producing Cells Coaxed to Multiply by Soluble Signal

November 8, 2022

Via: GEN

Insulin-producing β-islet cells in the pancreas can be made aware of a lack of insulin in the blood in a diabetes model, through signals relayed by a soluble signaling molecule called T-cadherin, report scientists at the University of Osaka in […]


Clinical Trials, Research and Development

Amgen to test new way to lower heart risk with large drug trial

November 7, 2022

Via: Biopharma Dive

Amgen is betting an experimental medicine it’s developing could become a new way to lower the risk of heart attack and stroke, beyond the lipid-lowering medicines like statins that have been the foundation of cardiovascular care for decades. Called olpasiran, […]


News

Artificial Intelligence for better antibody drugs: ready for prime time?

November 7, 2022

Via: Pharmaphorum

Artificial Intelligence (AI) and deep learning have already transformed several aspects of small molecule drug design. Recent advances in the area are now also impacting more complex tasks, such as design and optimisation of antibodies. As a result, 2022 saw […]