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Tag: vaccines


Industry, Vaccines

mRNA Vaccine Provides Broad Protection against All Known Influenza Subtypes

November 29, 2022

Via: GEN

Researchers at the Perelman School of Medicine at the University of Pennsylvania have developed an experimental multivalent mRNA-based vaccine against all 20 known subtypes of influenza virus. Their approach differs from previous attempts to craft a universal flu vaccine, by […]


Clinical Trials, Industry, Research and Development, Vaccines

Overcoming the challenges of developing vaccines in an accelerated timeframe

November 21, 2022

Via: Pharmaphorum

The world responded to the crisis at unprecedented speed, as leaders and experts focused on different ways to operate and succeed within the constraints of a new dynamic. One standout success we have all benefitted from is vaccine development, with […]


Clinical Trials, Industry, Research and Development, Vaccines

Kids Born by C-Section May Have Weaker Response to Vaccines

November 16, 2022

Via: Drugs.com

Babies born via cesarean section may not mount as strong an immune response after some childhood vaccines compared to babies delivered vaginally, researchers suggest. Antibody levels can be checked in blood or saliva, and babies born vaginally had higher levels […]


Clinical Trials, Industry, Research and Development, Vaccines

Sanofi/GSK’s next-generation COVID-19 booster granted EC approval

November 14, 2022

Via: PMLiVE

Shipments of the Beta-targeting booster are ready to be distributed to European countries as per advance purchase agreements, the companies said in a statement, in time for autumn/winter COVID-19 vaccination campaigns. “Today’s approval validates our research in developing a novel […]


FDA, Regulations

FDA declines to review Brainstorm’s ALS therapy

November 11, 2022

Via: Biopharma Dive

The FDA’s choice marks the latest setback for the NurOwn program. When that key, late-stage clinical trial failed in late 2020, Brainstorm’s CEO Chaim Lebovits said the company was confident there would be a path forward for its medicine. Brainstorm […]


Industry, Vaccines

Sanofi, GSK claim their first COVID jab approval

November 11, 2022

Via: Pharmaphorum

The European Commission has backed the use of the companies’ adjuvanted VidPrevtyn Beta vaccine – which targets the Beta variant of SARS-CoV-2 – as a booster vaccine candidate on the back of two “immunobridging” trials comparing it with currently-approved jabs. […]


Clinical Trials, Research and Development

X Chromosome Inactivation Surprisingly Found in Diverse Cancers in Men

November 10, 2022

Via: GEN

Cancer cells acquire genetic changes that allow them to grow and proliferate unchecked. Researchers at the Dana-Faber Cancer Institute and colleagues have now found another difference between cancer cells and normal cells. The team analyzed public datasets comprising thousands of […]


Clinical Trials, FDA, Regulations, Research and Development

Regeneron’s Libtayo combination granted FDA approval for non-small-cell lung cancer

November 9, 2022

Via: PMLiVE

Specifically, the treatment is indicated for patients with no epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK) or ROS1 aberrations, and those eligible for treatment must either have metastatic or locally advanced tumours that are not candidates for surgical […]


FDA, Industry, Regulations, Vaccines

GSK’s respiratory syncytial virus older adult vaccine given Priority Review by FDA

November 2, 2022

Via: PMLiVE

Priority Reviews are granted by the FDA in response to applications for vaccines that, if approved, have the potential to offer significant improvements in the safety or effectiveness of the treatment or prevention of critical conditions when compared to standard […]


Industry, Vaccines

Pfizer says maternal RSV shot gives strong protection to newborns

November 1, 2022

Via: Pharmaphorum

The phase 3 MATISSE study of RSVpreF given to pregnant women in order to protect their babies after birth found that the vaccine had efficacy of 81.8% in preventing lower respiratory tract infections caused by RSV in the first 90 […]


Clinical Trials, Industry, Research and Development, Vaccines

Study of Rare Antibody Cocktail against Lassa Virus Could Bring Clinical Trial Closer

October 27, 2022

Via: GEN

A new study from scientists at La Jolla Institute for Immunology (LJI) has given researchers a guide to neutralizing the deadly Lassa virus (LSV) using a trio of rare antibodies isolated from survivors of Lassa virus infection. The LJI scientists […]


Industry, Pricing, Regulations, Vaccines

Pfizer plans considerable 2023 Comirnaty markup

October 24, 2022

Via: Pharmaphorum

For over two years now, the US government has been running its public vaccination campaign – the largest in American history – and has purchased all of the Covid vaccines administered in the States, including over 500 million doses from […]


FDA, Industry, Regulations, Vaccines

FDA OKs Novavax COVID Vaccine as First Booster Shot

October 20, 2022

Via: Drugs.com

Americans will now have another choice if they want a COVID booster shot. On Wednesday, the U.S. Food and Drug Administration approved Novavax Inc.’s protein-based vaccine as a first booster dose. Until now, it had only been approved as a […]


Clinical Trials, Industry, Research and Development, Vaccines

New study identifies gene associated with strong immune response to COVID-19 vaccines

October 19, 2022

Via: PMLiVE

The research provides some of the first evidence of a relationship between genetic factors and the way that people’s immune systems respond to COVID-19 vaccines. In the study, which was published in Nature Medicine, the researchers found that those carrying […]


Industry, Vaccines

Moderna and Gavi update COVAX supply deal to include variant-specific COVID-19 vaccines

October 18, 2022

Via: PMLiVE

The biotech and Gavi will cancel their existing supply deal for vaccines based on the original COVID-19 strain, which has led to the supply of nearly 70 million doses to the 92 Gavi COVAX Advance Market Commitment (AMC) low- and […]


Biotech, Industry

The demand for nanoparticles in drug formulation is rising

October 17, 2022

Via: Biopharma Dive

Demand for nanoparticles in the biopharmaceutical industry is on the rise. Production of these tiny particles, which can protect and deliver medicines and vaccines where they need to go in the body, has been increasing since 1989. Over the last […]


Industry, Vaccines

Takeda Dengue Vaccine Recommended for Approval by European Committee

October 17, 2022

Via: GEN

Over half of the world’s population—nearly four billion people—are at risk of contracting dengue annually. The incidence of dengue has grown dramatically around the world in recent decades, causing an estimated 390 million infections and 500,000 hospitalizations annually. The rise […]


Industry, Vaccines

Pfizer/BioNTech BA.4/BA.5 COVID-19 booster approved for emergency use by FDA in children five to 11 years

October 13, 2022

Via: PMLiVE

The bivalent vaccine contains mRNA encoding the original SARS-CoV-2 spike protein – present in the original Pfizer/BioNTech COVID-19 vaccine – together with mRNA encoding the spike protein of the Omicron BA.4/BA.5 subvariants. The booster has already been granted EUA by […]


Clinical Trials, Industry, Research and Development, Vaccines

AstraZeneca’s intranasal COVID vaccine fails first clinical test

October 11, 2022

Via: Pharmaphorum

The 30-subject study – funded by AZ and published in the Lancet journal eBioMedicine – tested two strengths of the current formulation of the vaccine administered as a nasal spray, with half the group receiving a second intranasal dose 28 […]


Industry, Mergers and Acquisitions, Vaccines

Ziphius vaccines and UZ Ghent establish vaccine collaboration

October 7, 2022

Via: Pharma Times

Ziphius Vaccines – a company developing vaccines and therapeutics based on self-amplifying RNA (saRNA), and UZ Ghent – have announced that they have entered a public-private collaboration. The link-up involves the scale up and manufacturing of prophylactic self-amplifying RNA vaccines […]