Leptospirosis is a bacterial disease caused by bacteria of the genus Leptospira. In humans, it can cause a wide range of symptoms. However, some infected persons may have no symptoms at all. Without treatment, Leptospirosis can lead to kidney damage, meningitis (inflammation of the membrane around the brain and spinal cord), liver failure, respiratory distress, and even death. Now, scientists at Yale School of Public Health have designed a single-dose universal vaccine that could potentially protect against the many forms of leptospirosis bacteria.