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Novel cancer-fighting gene therapy enters phase I clinical trial

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells. The safety of the novel therapy is now being tested on patients with bone marrow cancer in a phase I clinical trial.

A new cancer-fighting gene therapy has been applied in the clinic for the first time after 20 years of preliminary research in the laboratories of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and Charité – Universitätsmedizin Berlin. Other initiatives to have emerged from this work include biotech start-up T-knife.

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