Staphylococcus aureus bacteria can be either a harmless resident of human skin, with one in four people harboring Staphylococcus aureus bacteria on their skin and mucous membranes of the upper respiratory tract, or a major pathogen wreaking havoc on our body. A Staph infection can lead to skin inflammation, lung infections, and can even lead to sepsis. The underlying mechanisms of how infectious inflammation is resolved by the host immune system are incompletely understood.
One hallmark of inflammation resolution is the activation of specialized pro-resolving mediators (SPMs) that enhance bacterial clearance and promote tissue repair.
