The brains of people with Down syndrome (DS) develop the same neurodegenerative tangles and plaques that are associated with Alzheimer’s disease (AD), and individuals with DS commonly exhibit signs of the neurodegenerative disorder in their forties or fifties. A new study from researchers at UC San Francisco (UCSF) has now shown that the tau tangles and plaques in DS are driven by the same amyloid beta (Aß) and tau prions that are implicated in AD.
