Agenus Inc. (NASDAQ: AGEN), an immuno-oncology company with an extensive pipeline of checkpoint antibodies, cell therapies, adjuvants, and vaccines designed to activate immune response to cancers and infections, today announced positive preliminary results from its Phase 1 trial of iNKT cell therapy in patients with moderate to severe symptoms of COVID-19 through its subsidiary, AgenTus Therapeutics.
AgenTus is actively accruing and treating patients with severe symptoms of COVID-19 with its proprietary allogeneic iNKT cell therapy, with dose escalation underway. Preliminary data show that of the 4 patients dosed to date, 3 patients (75%) were extubated and released after treatment. Notably, 2 of these patients (50%) were extubated within 24 hours of dosing.
