GNAO1 (G Protein Subunit Alpha O1) is a protein-coding gene. Most patients with a GNAO1 neurodevelopmental disorder are diagnosed as infants or young children and the first GNAO1 patients were only identified in 2013. Scientists are still uncovering the spectrum of symptoms and impacts from mutations in GNAO1. Now, a new study by scientists from the University of Geneva (UNIGE) has found that a mutation in GNAO1 leads to the replacement of one amino acid by another in the protein sequence. They also found that a zinc molecule may partially restore the functioning of the protein affected by these mutations.
