On June 12, 2020, the International Coalition of Medicines Regulatory Authorities (ICMRA) met for the fifth time in a virtual meeting moderated by FDA’s Janet Woodcock, director of the Center for Drug Evaluation and Research, to discuss policy approaches to the COVID-19 pandemic. The group reviewed the principals for COVID-19 clinical trials and prioritization of compounds. Concerns about the discontinuation of clinical trials and the number of underpowered studies were expressed by the group. The use of COVID-19 clinical trial master protocols to accelerate treatment development was also discussed. The group is working to compare master protocols from different countries to identify possible overlaps.