Tissue Engineering

Aspen’s Parkinson’s Cell Therapy Faces the Test of Translation
Biotech & Bioprocessing Aspen’s Parkinson’s Cell Therapy Faces the Test of Translation

Aspen Neuroscience’s sasineprocel starts with cells collected from a patient’s skin and aims to rebuild a population of neurons lost in Parkinson’s disease. To advance clinical testing, the company has raised $140.6 million through an initial public offering. The program now has to answer a central

Human Amniotic Membrane Advances in Regenerative Medicine
Research & Development Human Amniotic Membrane Advances in Regenerative Medicine

Injectable amniotic membrane powder is being investigated for its disease-modifying potential in treating osteoarthritis, as it contains factors that suppress enzymes responsible for cartilage breakdown. This transition from a specialized tool in ophthalmology to a cornerstone of orthopedics and

Therapeutic Ultrasound Mechanisms in Skin Repair and Regeneration
Tech & Innovation Therapeutic Ultrasound Mechanisms in Skin Repair and Regeneration

Addressing the chronic ischemia found in diabetic ulcers requires the upregulation of vascular endothelial growth factor, a process achievable through ultrasound-microbubble therapy. The skin functions as a highly sophisticated, multi-layered organ that maintains a constant state of flux, balancing

THUMPIN’ Initiative Aims to Bioengineer Living Hearts for Infants
Biotech & Bioprocessing THUMPIN’ Initiative Aims to Bioengineer Living Hearts for Infants

The partnership between clinical leaders at Harvard and manufacturing experts at Landmark Bio aims to bridge the gap between laboratory breakthroughs and clinical-grade therapies. For infants born with complex congenital heart defects, the current medical standard often involves a harrowing series

Bioprinted Living Nerve Conduits Show Promise for Nerve Repair
Biotech & Bioprocessing Bioprinted Living Nerve Conduits Show Promise for Nerve Repair

Engineering a synthetic alternative to natural nerve grafts requires a complex balance of structural durability, nutrient diffusion, and precise biological signaling. When peripheral nerves are severed, the internal fibers often lose their way, leading to permanent loss of sensation and motor

Can Stemden Replace Root Canals With Dentin Regeneration?
Research & Development Can Stemden Replace Root Canals With Dentin Regeneration?

Root canal therapy effectively prevents the spread of infection but strips a tooth of its sensory integrity and its ability to respond to future biological stress. For decades, the primary clinical paradigm has been centered on the replacement of organic loss with inorganic materials, a process

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