The development of synthetic intramembrane proteolysis receptors (SNIPRs) engineered by researchers in the United States could be a game-changer for CAR T-cell cancer therapies. This groundbreaking advancement introduces a novel methodology to enhance the precision and safety of CAR T-cell
Triple-negative breast cancer (TNBC) is known for its aggressive nature and limited treatment options. However, a recent breakthrough in personalized immunotherapy offers new hope for patients. Researchers have developed a neoantigen DNA vaccine platform that has shown promising results in
The U.S. Department of Energy's Argonne National Laboratory has been awarded two substantial grants totaling up to $21.7 million from the Advanced Research Projects Agency for Health (ARPA-H), a branch of the Department of Health and Human Services. These significant funds are poised to leverage
The discovery of a critical mechanism involving the protein USP39 has opened new avenues for understanding and potentially treating diseases like retinitis pigmentosa and certain cancers. Researchers have revealed that USP39 plays a crucial role in maintaining the stability of spliceosome subunits
In a significant move for the oncology field, ARTBIO, Inc. has entered into a groundbreaking partnership with 3B Pharmaceuticals GmbH that aims to advance a novel alpha radioligand therapy for treating solid tumors. ARTBIO, known for its innovative AlphaDirect™ platform, focuses on 212Pb-based
In a recent pivotal study published in Nature Communications, scientists have made significant strides in understanding the genetic underpinnings of testicular cancer, offering profound insights into its development and unveiling potential treatment strategies. This comprehensive research aims to