Scientists have used single-cell sequencing to generate an atlas of the human skin from both developing and adult sources, identifying differences and similarities across heterogeneous populations of skin cells. This highly detailed map of skin reveals that cellular processes from development are re-activated in cells from patients with inflammatory skin disease. In addition, it uncovered that skin from eczema and psoriasis patients share many of the same molecular pathways as developing skin cells. This offers potential new drug targets for treating these painful skin diseases.
