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SARS-CoV-2 vaccination creates a strong, persistent T-cell response

December 23, 2021


Scientists have harnessed T cells to better understand the immune response to mRNA vaccines against SARS-CoV-2, the virus that causes COVID-19. The findings from St. Jude Children’s Research Hospital and Washington University in St. Louis were published today in Cell.

The findings suggest that some aspects of the immune response to mRNA vaccines remain robust six months after vaccination.

Much of the research on immune response to mRNA vaccination has focused on antibody levels, which can be measured by a blood test. However, this is just one aspect of immunity. Researchers wanted to better understand the specificity and structure of the T-cell response to vaccination.