Research & Development

Moderate Coffee Tied to Longer Telomeres in Mental Disorders
Research & Development Moderate Coffee Tied to Longer Telomeres in Mental Disorders

A daily habit as ordinary as pouring a third or fourth cup of coffee may have aligned with a five-year edge in biological aging among people living with schizophrenia and mood disorders, hinting that moderation could matter more than any exotic supplement. The notion is surprising because coffee

Treg Priming vs. Broad Immunosuppression: A Comparative Analysis
Research & Development Treg Priming vs. Broad Immunosuppression: A Comparative Analysis

When a lifesaving transplant risks unleashing the very immune fire meant to cure leukemia, choices about how to steer immunity before donor cells arrive determine whether patients heal or face harm. That dilemma sits at the heart of allogeneic hematopoietic stem cell transplantation, where

Can Romidepsin Revive Chemo in Relapsed Neuroblastoma?
Research & Development Can Romidepsin Revive Chemo in Relapsed Neuroblastoma?

Jan Kaiserle sits down with Ivan Kairatov, a biopharma expert deeply versed in molecular therapeutics and translational research, to discuss a new approach to overcoming treatment resistance in neuroblastoma. Drawing on work published in Science Advances in 2025, Kairatov explains how a failed

Fungi in Cancer: From Tumor Ecology to Targeted Therapies
Research & Development Fungi in Cancer: From Tumor Ecology to Targeted Therapies

If bacteria aren’t the whole story of the tumor microenvironment, what crucial signals are being missed from fungi that quietly occupy the same space yet account for only a sliver of the sequencing reads but a disproportionate share of immune cues and clinical outcomes? That challenge has gained

Can Sac-TMT Plus Keytruda Redefine First-Line Lung Cancer?
Research & Development Can Sac-TMT Plus Keytruda Redefine First-Line Lung Cancer?

Julia Lainster sits down with Ivan Kairatov, a seasoned biopharma leader with deep experience in oncology R&D, to unpack the latest data from OptiTROP-Lung05 and what it could mean for first-line NSCLC. They explore how a TROP2-directed antibody-drug conjugate combined with an immune checkpoint

How Will CNPV Transform Biopharma Drug Approvals?
Research & Development How Will CNPV Transform Biopharma Drug Approvals?

In a world where patients often wait nearly a year for life-saving drugs to gain approval, a groundbreaking initiative by the FDA is slashing that timeline to mere weeks, promising a dramatic shift in biopharma. The Commissioner’s National Priority Voucher (CNPV) pilot program is not just speeding

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