In the relentless pursuit of enhanced cancer treatments, recent research has shed light on the dual inhibition of MYCN and MDM2 as a promising strategy. Both MYCN and MDM2 are vital oncogenes implicated in various tumorigenic processes. Their simultaneous targeting might revolutionize the
Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, with drug-resistant strains posing a significant challenge to global health. Recent advancements in TB treatment, particularly for drug-resistant forms, offer new hope. This article explores the potential of new drug
New research shines light on position-specific hallmarks of cancer, diving deeply into the contemporary understanding of cancer and focusing on the specific expression patterns of cancer hallmarks within tumors. The fundamental question it addresses is, "What is a tumor?"—a crucial query when
Imagine a future where birth injuries, facial defects, and other cartilage-related conditions could be treated effectively and efficiently with a novel tissue that combines softness, elasticity, and stability. This future has moved significantly closer to reality with the discovery of a new
Prostate cancer screening has long relied on blood tests, MRIs, and biopsies, each carrying its own set of drawbacks, such as causing discomfort and leading to the overdiagnosis of low-grade cancers that might not pose significant health risks. These traditional approaches, while effective in
Recent research led by scientists at Scripps Research has unveiled groundbreaking insights into the structure and behavior of the protein transthyretin, which could have significant implications for the treatment of transthyretin amyloidosis (ATTR). This disease, marked by the misfolding of