Research & Development

Advancements in Targeted Therapies for PIK3CA-Mutated Cancers
Research & Development Advancements in Targeted Therapies for PIK3CA-Mutated Cancers

Recent scientific advancements have shed new light on the implications of PIK3CA mutations in cancer treatment, prompting significant interest in developing targeted therapies to enhance drug efficacy while mitigating adverse effects. The PIK3CA gene, which encodes the p110α subunit of

Can Ivonescimab and Pfizer's ADCs Transform Cancer Treatment?
Research & Development Can Ivonescimab and Pfizer's ADCs Transform Cancer Treatment?

Key players in the pharmaceutical landscape, Summit Therapeutics and Pfizer, are embarking on a noteworthy collaboration to test out Summit’s experimental immunotherapy, ivonescimab, combined with Pfizer’s sophisticated antibody-drug conjugates (ADCs) in upcoming clinical trials targeting specific

Research Priorities Set to Improve Appendiceal Cancer Understanding and Treatment
Research & Development Research Priorities Set to Improve Appendiceal Cancer Understanding and Treatment

Appendiceal cancer, a rare malignancy, presents significant challenges due to the lack of standardized screening guidelines, identifiable risk factors, and a common tumor classification system. These hurdles often result in delayed diagnoses and poor prognoses for patients. The estimated annual

How Do Environmental Factors Impact Human Aging and Premature Mortality?
Research & Development How Do Environmental Factors Impact Human Aging and Premature Mortality?

Human aging is a complex process influenced by a combination of genetic and environmental factors. While the role of genetics has been widely studied, recent research highlights the significant impact of environmental exposures on aging and premature mortality. This article delves into the findings

Innovative Alternatives Sought After Cancer Trial Yields Disappointing Results
Research & Development Innovative Alternatives Sought After Cancer Trial Yields Disappointing Results

In a significant effort to find alternative treatments for head and neck cancer patients who cannot use cisplatin due to its harmful side effects, researchers conducted a new clinical trial that unfortunately provided discouraging results. Cisplatin is a widely used chemotherapy drug known for its

Cancer Cells Cooperate to Secure Nutrients, Revealing New Treatment Targets
Research & Development Cancer Cells Cooperate to Secure Nutrients, Revealing New Treatment Targets

Cancer biology has traditionally emphasized the competitive nature of tumor cells as they compete fiercely for limited resources. However, recent research led by Carlos Carmona-Fontaine at New York University has unveiled a groundbreaking and surprising discovery that cancer cells also exhibit

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