Despite a plethora of interventions, including diet, exercise, and medications, obesity continues to be a significant health problem. The fight against obesity currently involves substantial trial-and-error, out-of-pocket costs, and adverse effects. Obesity medications cause gastrointestinal side effects in nearly 73% of patients.
Molecular predictors of response to obesity treatment are key in combating the obesity epidemic. Toward this end, the National Institutes of Health (NIH) launched ADOPT (Accumulating Data to Optimally Predict Obesity Treatment Core Measures) in 2018 which collects behavioral, biological, environmental, and psychosocial data to identify predictors of response to obesity treatment.
