A team from Trinity College Dublin says it has developed a new, machine learning-based technique to accurately classify the state of macrophages. Classifying macrophages is important because they can modify their behavior and act as pro- or anti-inflammatory agents in the immune response, according to the researchers.
As a result, the work has a suite of implications for research and has the potential to one day make major societal impact. For example, this new approach could be of use to drug designers looking to create therapies targeting diseases and auto-immune conditions such as diabetes, cancer, and rheumatoid arthritis—all of which are impacted by cellular metabolism and macrophage function.
