Researchers used metal-organic frameworks (MOFs) enhanced with a green tea phytochemical coating to target human prostate cancer cells for the first time.
The new method for deploying the genetic snipping tool directly into target cells is a big step towards more effective, safer and cheaper gene therapy with treatment potential for multiple genetic disorders.
Lead researcher, Associate Professor Ravi Shukla, said MOFs, which are versatile and biocompatible nanomaterials, were a promising alternative to existing viral methods for delivering the gene editing tool CRISPR/Cas9.
