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Moderna or Pfizer? One COVID Shot May Be Safer for Older Adults

August 3, 2023


While both the Moderna and Pfizer COVID-19 vaccines are considered safe and highly effective, new research finds the Moderna shot has been the safest and most effective for seniors.

“The results of this study can help public health experts weigh which mRNA vaccine might be preferred for older adults and older subgroups, such as those with increased frailty,” said lead study author Daniel Harris. He is an epidemiologist and research scientist in the Center for Gerontology and Healthcare Research at Brown University’s School of Public Health, in Providence, R.I.

Researchers compared the two vaccines head-to-head in more than 6 million older adults included in the study.