Pancreatic cancer is an incurable form of cancer, and gene therapies are currently in clinical testing to treat this deadly disease. A comprehensive review of the gene and cell biotherapies in development to combat pancreatic cancer is published in the peer-reviewed journal Human Gene Therapy.
The article titled “Pancreatic Cancer Cell and Gene Biotherapies: Past, Present and Future,” contributed by corresponding author Pierre Cordelier, from the University of Toulouse, and coauthors, describes the ongoing gene therapy clinical trials. In addition to gene therapies, the authors discuss vaccines, chimeric antigen receptor (CAR)-T cell therapy, suicide genes, and oncolytic viruses
“Breaking the code of pancreatic tumours rather than using brute force will help in defeating this currently incurable disease,” state the authors.
