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Charles River Launches pHelper Offering for AAV-based Gene Therapies

March 9, 2023

Charles River Laboratories International, Inc. has launched its off-the-shelf pHelper offering, which is designed to secure supply and streamline adeno-associated virus (AAV)-based gene therapy programs from early discovery through commercial manufacturing. It is available in Research Grade (RG), High Quality (HQ), and Good Manufacturing Practice (GMP)-grade.

Helper plasmids are the latest in a comprehensive collection of contract development and manufacturing organization (CDMO) products and services developed to help simplify complex supply chains and safeguard viral vector packaging in cell and gene therapy programs. This plasmid product is manufactured and released with Chemistry, Manufacturing and Controls (CMC) information and a Certificate of Analysis (COA) to support regulatory filings and approval applications.

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