In an exclusive interview with GEN, Sakis Mantalaris, PhD, professor of biomedical systems engineering at the Georgia Institute of Technology, explained that identifying metabolic biomarkers could help cell therapy developers speed up and optimize their manufacturing processes.
“If you identify and use biomarkers then, as we’ve shown in theory and to some extent in practice, you can have a very fast bioprocess,” he said.
Mantalaris, who gave a talk at the Bioprocessing Summit, pointed out that he has shown that cell metabolism changes more dynamically than protein or gene expression during bioprocessing.
