Genetic Analysis

Comprehensive TPMT Genotyping Urged To Predict Thiopurine Drug Response
Research & Development Comprehensive TPMT Genotyping Urged To Predict Thiopurine Drug Response

Mayo Clinic researchers have made a case for comprehensive TPMT genotyping across various ancestries to better predict drug response and minimize adverse reactions. Their recent discovery of the TPMT∗8 allele, a gene variant associated with reduced metabolism of thiopurine drugs, has revolutionary

How Are Genetic Challenges Impacting H5N1 Avian Flu Detection?
Research & Development How Are Genetic Challenges Impacting H5N1 Avian Flu Detection?

In an intriguing development, a genetic analysis was performed on an H5N1 avian flu infection detected in a child from California in November, leading to significant findings and presenting several challenges. The US Centers for Disease Control and Prevention (CDC) announced that the virus RNA

Can Gene Therapy Offer a Breakthrough for Alzheimer’s Treatment?
Research & Development Can Gene Therapy Offer a Breakthrough for Alzheimer’s Treatment?

Alzheimer’s disease, a debilitating condition marked by progressive memory loss and cognitive decline, has long proven resistant to effective treatment, leaving millions of patients and their families searching for hope. Despite significant research efforts, traditional therapies targeting the

How is Estonia's Biobank Revolutionizing Precision Medicine?
Tech & Innovation How is Estonia's Biobank Revolutionizing Precision Medicine?

In recent years, health research has been undergoing two major, yet seemingly opposing, shifts: a deep dive into individual-centric medicine and a broadened focus on population-wide studies. On the individual level, advancements in genomics are driving the shift toward personalized medicine, where

Breakthrough Gene Therapy Could Prevent Premature Births Worldwide
Research & Development Breakthrough Gene Therapy Could Prevent Premature Births Worldwide

A groundbreaking gene therapy showing promise in preventing premature births and treating placental growth insufficiency holds the potential to significantly improve pregnancies worldwide. This revolutionary therapy is being developed by a dedicated team led by Dr. Helen N. Jones from the

Can Innovative Approaches Overcome Gene Therapy’s Persistent Challenges?
Research & Development Can Innovative Approaches Overcome Gene Therapy’s Persistent Challenges?

Gene therapy has made remarkable strides in recent years, with 20 approved indications in the United States and a record number of approvals in 2023. Investigational trials are rapidly increasing across various diseases, including hemophilia B, sickle cell disease, and Duchenne muscular dystrophy.

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