The groundbreaking research conducted by Van Andel Institute scientists sheds new light on how developmental epigenetic changes can profoundly influence cancer risk later in life. The study, published in Nature Cancer, identifies two distinct epigenetic states formed during development, which are
The potential breakthrough in treating liver cirrhosis caused by metabolic dysfunction-associated steatohepatitis (MASH) has come from a recent study by Akero Therapeutics. Efruxifermin, an experimental drug, has shown significant promise in reversing liver damage in patients suffering from this
Genetic testing for Lynch Syndrome (LS) is crucial in preventing certain cancers, especially for women diagnosed with endometrial (womb) cancer. This inherited condition significantly raises the lifetime risk of various cancers, including bowel, ovarian, pancreatic, and womb cancers. Despite
Every 40 seconds, someone in the United States experiences a stroke, and ischemic strokes are the most common type. Unfortunately, only about 5% of ischemic stroke survivors fully recover, while many endure long-term complications such as weakness, chronic pain, or epilepsy. Given these concerning
The role of an 18th-century instrument maker, Francis Hauksbee the Younger, may have been pivotal in shaping the landscape of modern clinical trials. His contributions possibly influenced James Lind, a Royal Navy surgeon, whose pioneering controlled trial helped identify vitamin C as an effective
The University of Kentucky (UK) researchers are currently engaged in a groundbreaking clinical trial aimed at exploring the potential benefits of medical cannabis in managing symptoms of late-stage dementia. This study, officially named the LiBBY Study, is backed by both the National Institutes of