Recent research led by scientists at Scripps Research has unveiled groundbreaking insights into the structure and behavior of the protein transthyretin, which could have significant implications for the treatment of transthyretin amyloidosis (ATTR). This disease, marked by the misfolding of
The groundbreaking research conducted by Van Andel Institute scientists sheds new light on how developmental epigenetic changes can profoundly influence cancer risk later in life. The study, published in Nature Cancer, identifies two distinct epigenetic states formed during development, which are
The potential breakthrough in treating liver cirrhosis caused by metabolic dysfunction-associated steatohepatitis (MASH) has come from a recent study by Akero Therapeutics. Efruxifermin, an experimental drug, has shown significant promise in reversing liver damage in patients suffering from this
Genetic testing for Lynch Syndrome (LS) is crucial in preventing certain cancers, especially for women diagnosed with endometrial (womb) cancer. This inherited condition significantly raises the lifetime risk of various cancers, including bowel, ovarian, pancreatic, and womb cancers. Despite
Every 40 seconds, someone in the United States experiences a stroke, and ischemic strokes are the most common type. Unfortunately, only about 5% of ischemic stroke survivors fully recover, while many endure long-term complications such as weakness, chronic pain, or epilepsy. Given these concerning
The role of an 18th-century instrument maker, Francis Hauksbee the Younger, may have been pivotal in shaping the landscape of modern clinical trials. His contributions possibly influenced James Lind, a Royal Navy surgeon, whose pioneering controlled trial helped identify vitamin C as an effective
