Brief overview of the CGT landscape
A useful starting point is to understand the different types of CGTs. The following are the definition of the three types:
Cell therapies: involves the transfer of intact, live cells into a patient to treat or cure a disease (autologous: from the patient; allogeneic: from a donor). CAR-T therapies fall into this category.
Gene therapies: the transfer of genetic material to prevent or treat disease; this genetic material changes how a cell manufactures a single protein or group of proteins.
mRNA vaccines. These broadly fit into the CGT category, such as the COVID-19 vaccines from Pfizer-BioNTech and Moderna, as well as other mRNA-based therapies being developed.