Although the U.S. Centers for Disease Control and Prevention (CDC) reports a recent decline in HIV incidence rates, this is largely due to advances in prevention and care. A vaccine against HIV has not been developed, four decades since the discovery if the virus.
A new study reports the development of a unique native-like trimer (NLT) conformation of the HIV envelop that can generate neutralizing antibodies against difficult to neutralize HIV (tier-2) strains in mice.