Insilico Medicine, a clinical-stage company leveraging generative artificial intelligence (AI) for drug discovery and development, has announced promising results for its novel drug, ISM5411, aimed at treating Inflammatory Bowel Disease (IBD). This gut-restricted and PHD-specific inhibitor was
Glioblastoma, an aggressive and often fatal form of brain cancer, has long posed a formidable challenge to medical professionals. With an average lifespan of 12 to 15 months post-diagnosis and a mere 5% survival rate five years after diagnosis, the need for innovative treatments has never been more
Penn Medicine’s Center for Cellular Immunotherapies (CCI) is at the forefront of revolutionizing cancer treatment through CAR (chimeric antigen receptor) T cell therapy. This innovative approach harnesses the power of the patient’s own immune system to target and destroy cancer cells, offering new
The detection and segmentation of brain tumors in MRI images present a critical challenge in medical diagnostics, given their implications for patient treatment plans and outcomes. Despite advancements in imaging techniques and manual segmentation methodologies, the need for precise, automated
Acute respiratory infections are a significant cause of both morbidity and mortality in young children globally, with an especially pronounced impact in low- and middle-income countries on children under five years old. Among the array of pathogens responsible for these illnesses, human
Asthma is the most prevalent chronic respiratory disease in children, disproportionately affecting racially and ethnically minoritized populations in the United States. Puerto Rican and non-Hispanic Black youths, in particular, experience higher rates of emergency department visits due to asthma
Researchers at the National University of Singapore (NUS) have developed an innovative method to enhance the effectiveness of chemotherapy while mitigating its adverse side effects. This novel approach employs brief, localized pulses of magnetic fields, which significantly increase the uptake of
The digital age has brought about a myriad of tools and resources aimed at providing support for families of children with neurodevelopmental disorders such as autism and ADHD. These conditions, impacting one in ten children, pose significant challenges to development, behavior, and overall
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory condition that profoundly impacts patients' quality of life and incurs substantial healthcare costs. Effective management of COPD often necessitates the use of inhaled medications, such as corticosteroids, long-acting
Gene therapy has emerged as a promising frontier for treating a range of genetic disorders, but effectively delivering therapeutic genes to the kidneys remains a significant challenge. Researchers at the Oregon Health & Science University School of Medicine have been delving into the complex domain
