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Solid Biosciences acquires AavantiBio, conducts $75 million private placement

October 4, 2022

AavantiBio, a precision genetic medicine company that was bankrolled by Solid’s rival Sarepta back in 2020, focuses on neuromuscular and cardiac rare diseases. Its key assets include product candidates for Duchenne muscular dystrophy (DMD), Friedreich’s ataxia, and BAG3 mediated dilated cardiomyopathy, among others.

Once combined, the next step is to advance a portfolio of neuromuscular and cardiac programs for those diseases with indications Solid Biosciences believes have a high unmet need. This will be led by Solid’s differentiated, adeno-associated virus (AAV) gene transfer therapy candidate, SGT-003, for treatment of DMD. Additional pipeline programs will include AavantiBio’s AVB-002, a gene transfer candidate for treating Friedrich’s ataxia (FA), and AVB-401 for BAG3 mediated dilated cardiomyopathy.

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