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New needle-free nasal vaccine shows promise for COVID-19

July 28, 2022


New research shows that a needle-free mucosal bacteriophage (phage) T4-based COVID-19 vaccine is effective against SARS-CoV-2 infection. The findings were published in mBio, an open access journal of the American Society for Microbiology.

In recent years, the Food and Drug Administration authorized mRNA- and adenovirus-based SARS-CoV-2 vaccines. These vaccines are intramuscularly injected in 2 or more doses and are effective in preventing COVID-19, but they do not induce efficient mucosal immunity or prevent viral transmission.

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