New research led by scientists at the University of Sheffield’s Neuroscience and Healthy Life Span Institutes demonstrates that oxidative breaks form and are repaired in “junk” DNA. The findings may lead to the development of therapeutic treatments for neurological disorders such as dementia, and Alzheimer’s disease, and may have implications for future cancer treatments.
The findings are published in the journal Nature in a paper titled, “A mechanism for oxidative damage repair at gene regulatory elements.”
