Grand River Aseptic Manufacturing (GRAM), a parenteral drug product contract development and manufacturing organization (CDMO), has entered into an agreement with Bavarian Nordic, a Denmark-based vaccine company, to fill and finish JYNNEOS smallpox/monkeypox vaccine. The agreement was supported by the Department of Health and Human Services (HHS) and the Biomedical Advance Research and Development Authority (BARDA) to increase domestic vaccine supply.