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Amgen, AstraZeneca dig into data from phase 3 asthma trial, emerging with evidence of efficacy in hard-to-treat subgroup

September 7, 2021

Piece by piece, Amgen and AstraZeneca are building the case for their potential asthma blockbuster. The latest brick to fall into place comes from a new slice of phase 3 data, which suggests tezepelumab may be particularly effective in a subgroup of severe asthma patients.

The pre-specified exploratory analysis comes from a phase 3 clinical trial that linked tezepelumab to statistically significant reductions in exacerbations in asthma patients, including individuals with low counts of a white blood cell who have limited treatment options. The exploratory analysis points to the potential for tezepelumab to move the needle in another hard-to-treat subgroup of patients.

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