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Allergen builds case for first drug therapy for presbyopia

July 26, 2021

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Now, there could be another alternative, in the form of eye drops administered daily, according to AbbVie’s Allergan subsidiary, which reported new phase 3 data for its pilocarpine formulation – codenamed AGN-190584 – at the American Society of Cataract and Refractive Surgery (ASCRS) congress over the weekend.

Pilocarpine is a muscarinic cholinergic agonist that is already used to reduce pressure inside the eye in ophthalmic diseases like glaucoma, but has only recently been repurposed for the long-sightedness – caused by a stiffening of the lens – that develops in people after the age of 40.

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